Four studies provided the mean age of the participants, all between 60 and 65 years, and the HR for their combined analysis was 0.56, which also failed to reach statistical significance (95% CI: 0.31–1.02, p overall effect = 0.057) [ 21 , 22 , 23 , 33 ].
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Effects of Metformin on Risk and Prognosis of Biliary Tract Cancer: A Systematic Review and Meta-Analysis.
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