Novel Therapeutic Approaches to Invasive Candidiasis: Considerations for the Clinician.

68 , 70 It is noteworthy that the comparator echinocandin in these studies demonstrated better results, although the differences did not reach statistical significance. 68 , 70 However, (fos-)manogepix was effective against echinocandin-resistant ( FKS -mutant) C. albicans and C. glabrata , while the comparator echinocandin was not. 68 , 71 (Fos-)manogepix was also effective in murine models of C. auris IC. 72 , 73 In a murine model of IAC, repeated doses of fosm

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