Older age should not be a barrier to testing for somatic variants in homologous recombination DNA repair-related genes in patients with high-grade serous ovarian carcinoma.

Transl Oncol · 2023 · PMC9971549 · PMID 36805919

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did not reach statistical significanceno p-value reported

As this dataset had a relatively smaller number of patients, results did not reach statistical significance, but comparison of the median ages does support the finding that somatic BRCA2 PVs occurred more frequently in older patients compared with BRCA1 .

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