Association of Intensive vs Standard Blood Pressure Control With Regional Changes in Cerebral Small Vessel Disease Biomarkers: Post Hoc Secondary Analysis of the SPRINT MIND Randomized Clinical Trial.

JAMA Netw Open · 2023 · PMC9978954 · PMID 36857053

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did not reach statistical significanceno p-value reported

In the previous analysis of the secondary outcomes, there was a small increase in GM CBF associated with intensive treatment compared with standard treatment that did not reach statistical significance, likely owing in part to these regional differences.

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