Weekly food intake was significantly higher in MC4R -TB compared to WT littermates as expected, and although not statistically significant, there was a strong trend toward reduced food intake in MC4R -TB mice that received AAV-Cre-GFP injection into the vSUB ( Fig. 6E , F ).
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Collateralizing ventral subiculum melanocortin 4 receptor circuits regulate energy balance and food motivation.
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