PPARG in TRPV1 flox/flox ; Cx3cr1 cre -ApoE4 mice also showed a trend toward downregulation (Fig. 2i ).
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TRPV1 regulates ApoE4-disrupted intracellular lipid homeostasis and decreases synaptic phagocytosis by microglia.
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PPARG in TRPV1 flox/flox ; Cx3cr1 cre -ApoE4 mice also showed a trend toward downregulation (Fig. 2i ).