Simvastatin Upregulates Lipoxin A4 and Accelerates Neuroinflammation Resolution After Intracerebral Hemorrhage.

Curr Neurovasc Res · 2022 · PMC9982195 · PMID 36100985

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Notably, animal models treated with simvastatin showed a trend similar to that of the LXA4 group, but the anti-edema effect of simvastatin on ICH was weakened by Boc-2, a selective FPR2 antagonist (Figs. 5A and B ).

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