Prasugrel-Based De-Escalation in Patients With Acute Coronary Syndrome According to Renal Function.

JACC Asia · 2023 · PMC9982221 · PMID 36873753

Europe PMC DOI

hedged sentences

0.0920

closest p · 1.8× alpha

0.0920

boldest claim

The sentences

did not reach statistical significanceP = 0.092so close (0.05 < p ≤ 0.1)

Impact of prasugrel de-escalation did not reach statistical significance in the high eGFR group (HR: 0.48; 95% CI: 0.21-1.13; P = 0.092).

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an increasing trendno p-value reported

The benefit of de-escalation for bleeding showed an increasing trend as renal function decreased.

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