–6 points with placebo; p = 0.016) but this improvement did not quite reach statistical significance at 6 weeks (mean –10.4 points from baseline in bupropion vs. –7.6 points with placebo; p = 0.108) [ 74 ].
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A Narrative Review of the Lesser Known Medications for Treatment of Restless Legs Syndrome and Pathogenetic Implications for Their Use.
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0.1080
0.1080
The sentences
Although there was a trend toward improvement in the level of activity and periodic limb movement while awake (PLMW) as measured by actigraphy and the mSIT, the results did not reach statistical significance (no scores or p-value provided), perhaps due to the small sample size and the known variability in these measures [ 50 ].