Synergistic Targeting of DNA-PK and KIT Signaling Pathways in KIT Mutant Acute Myeloid Leukemia.

Consistent with this, M3814 treatment reduced MYC phosphorylation at threonine 58, serine 62, and serine 164 ( supplemental Table S2 ); however, as a single-agent treatment, this did not reach statistical significance.

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