Salivary IgA subtypes as novel disease biomarkers in systemic lupus erythematosus.

Besides that, when the SLE group was segregated into inactive and active patients, we observed a clear trend towards increased IgA subtype levels in active SLE individuals.

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Remarkably, we only found positive and highly significant correlations between circulating anti-dsDNA with the salivary concentration of IgA1 ( Figure 3B ), IgA2 ( Figure 3C ), and tIgA ( Figure 3D ) in patients with SLE.

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