The SLC25A47 locus controls gluconeogenesis and energy expenditure.

Proc Natl Acad Sci U S A · 2023 · PMC9992842 · PMID 36812201

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Similarly, the expression of Mdh2 , which catalyzes the conversion between OAA and malate in the mitochondria, was significantly elevated in the liver of Slc25a47 Alb-Cre mice, whereas the expression of Mdh1 , the cytosolic form, showed a trend of down-regulation.

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