Lower heart rates and beta-blockers are associated with new-onset atrial fibrillation.

3.2.5 Beta-blocker and new-onset atrial fibrillation The likelihood of developing AF on beta-blockers over the course of the study was 34.1% vs 27.4% in participants without beta-blockers, although this did not reach statistical significance in this smaller subset (hazard ratio 1.342 [CI 0.842, 2.137], p = 0.221). 3.3 SPRINT 3.3.1 Heart rate and new-onset atrial fibrillation AF was detected in 120 participants (1.6%) of the SPRINT cohort during follow up.

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