IL-10 modified mRNA monotherapy prolongs survival after composite facial allografting through the induction of mixed chimerism.

Mol Ther Nucleic Acids · 2023 · PMC9996371 · PMID 36910717

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showed a trendno p-value reported

In facial OMC allografts, a single 10 μg dose of IL-10 modRNA showed a trend toward decreased Th17 cells (4.5%) and increased Th2 cells (10.5%) compared with the buffer group (Th17, 7.3%; Th2, 3.5%), but not significantly.

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