Barely Significant
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A novel rhein-huprine hybrid ameliorates disease-modifying properties in preclinical mice model of Alzheimer's disease exacerbated with high fat diet.

Cell Biosci · 2023 · PMC9999531 · PMID 36895036

Europe PMCDOI
1
hedged sentence
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closest p · 1.0× alpha
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boldest claim

The sentences

a positive trendP < 0.05actually significant
did not reach statistical significanceno p-value reported
A similar pattern was observed for the other synaptic proteins studied, but in the case of synaptophysin the values did not reach statistical significance, and only a positive trend was observed (Synaptophysin: APP/PS1 HFD SALINE vs APP/PS1 HFD RHE-HUP P < 0.05; Neurexin: WT CT SALINE vs APP/PS1 HFD SALINE p < 0.01; APP/PS1 HFD SALINE vs APP/PS1 HFD RHE-HUP p < 0.05) (Fig. 6 k).

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