Excerpts

Participants aged 15–34 yr and 35–49 yr showed a decreasing trend ( P <0.001) while those aged 50–64 yr and 65–80 yr showed an increasing trend ( P <0.001) between 2004 and 2013.

In this study, there was a significant difference between two groups regarding the requirement of propofol as rescue drug, with an increasing trend of using it in Group P ( P < 0.001).

The baseline and endpoint score differences for patients in each arm were highly significant (p<0.001).

One study 30 reported that the increased range of plantarflexion in the early controlled motion and weightbearing group at 3 and 6 months was not statistically significant, but the increased range of dorsiflexion in the early controlled motion and weightbearing group at 3, 6, and 12 months was highly significant ( P < .001).

3.3 Genetic structure Moderate but highly significant genetic differentiation ( F ST = 0.090, p < .001) was detected across the whole turbot distribution using the 755 SNP panel, mostly attributable to divergence between the more isolated areas (Black Sea and the Adriatic Sea) and the Atlantic Ocean and the Baltic Sea (Table 3 and Table S1 ).

Statistical correlation analyses were performed on more than 20 points collected on calcifications and indicate highly significant positive correlation for Ca and P (Pearson r: 0.9965; p ≤ 0.001), for Ca and Mg (Pearson r: 0.9646; p ≤ 0.002), and significant negative correlation for Ca and S (Pearson r: −0.8515; p ≤ 0.05).

All of these variables had highly significant p -values ( p < 0.001), indicating meaningful differences between clusters.

We found strong and highly significant negative correlations between time and HSN intensity (Spearman's ρ < −0.84, p < 0.001), time and SPN (ρ < −0.80, p < 0.001), time and TUG (ρ < −0.67, p < 0.001), and time and DHI (ρ < −0.94, p < 0.001) in both the groups.

In a multiple regression predicting the (absolute) difference between the two AUDIT scores, the participants’ age was highly significant, t (1,092)=6.23, p <0.001.

Two way repeated measures ANOVA revealed highly significant differences for treatment (F 2, 78 = 22.402, p < 0.001).

There was a statistically highly significant ( P <0.001) difference between nanoemulsion irrigants and normal particle size irrigants with ( P -value 0.00052).

The genotypic variance was highly significant ( P < 0.001) for all traits except for tofu weight.

Genotype As expected, genotype had a highly significant impact on myostatin concentrations (Fig. 1 ): homozygotes had lower mean plasma myostatin concentration than heterozygous horses (p < 0.001), and heterozygous horses had lower mean myostatin concentration than wild type horses (p < 0.001).

The effect of year fitted with the spline was highly significant for two species ( P. austriacus : df = 2.92, p < 0.001 and T. teniotis : df = 3.87, p = 0.026), suggesting a different inter-annual pattern among these species ( Figure 3 , Table 6 ). 4.

Although there was no significant association between ponesimod systemic exposure (AUC ss ) or PD end points (LC ss or ΔLC ss ) and ARRs, there was a highly significant association between CUALs and ARRs, resulting in a MVOF decrease of 34.838 points (df = 1, p < 0.001).

For chronic NOEC REACH data (European Commission 2006), the relationship with the chronic high‐quality nonextrapolated SSD midpoint data was less strong than for the EC50 data but still highly significant (A; overlapping number of compounds 251, y = 0.7448 x + 0.8502, R 2 = 0.60, p < 0.001).

Analysis of variance ( Appendix A.5 ) for the variable TH showed that the choice of device had a highly significant effect on the measured values (F = 591.9, p < 0.001).

Association of TSR with Clinico-Pathological Features There is a highly significant correlation between TSR with luminal ER+ histological tumour type and grade (both p < 0.001), but not for TNBC.

Spatial autocorrelation in PBBA II block occupancy data was highly significant (Z‐test, p ‐value < .001) for all six study species (Global Moran's I, mean = 0.33; Table 1 ).

For the overall physical score there was a highly significant change in time ( P < .001), with scores decreasing from baseline for all groups ( P < .05).

4 , upper panels), SAL-treated stressed animals showed a marked decrease, relative to SAL-treated controls, in exploration of the novel object, which was highly significant in both tests [t(1,30) = 3.85 and 4.47, p < 0.001].

They found a highly significant difference in both HPV-associated OPSCC DSS (log-rank p < 0.001) and PFS (log-rank p < 0.001), with higher TIL levels linked to longer survival.

The overall model was highly significant ( P < 0.001), that is, our model explained the development of CVD better than the null model (model with no explanatory variables), and provided the following cutoff points: optimal , 10 (square root = 0.343); discard , 7 (negative likelihood ratio = 0.07); and confirmation , 14 (positive likelihood ratio = 10.56).

The difference is highly significant (Mann-Whitney test: p<0.001).

After applying the logistic regression method, when adjusting odds ratios according to tobacco and alcohol consumption and the presence of stress, the association between cortisol levels and presence of stress was highly significant ( p <0.001).