Excerpts

Such an increase was slight due to the small size of malignant lesions but was highly significant in most experiments (e.g., in the AT-3 model at day 9 post-implantation, P < 0.0001; in the 4T1 model at day 9 post-implantation, P = 0.0029).

To statistically assess the overlap between the two gene sets, we performed a Fisher’s Exact test, which demonstrated a highly significant concordance (P < 0.0001, two-sided), indicating that the shared transcriptional response is unlikely to occur by chance (Supplementary Table S1 ).

The comparison of 289 pairs of exon and upstream intron produced a highly significant correlation ( r = 0.3013, p < 0.0001; Figure 4 ), similar to the correlation obtained for the whole genes.

Furthermore, the analysis indicates that the dsRNA construct also had a highly significant impact (p < 0.0001, Figure 3C ).

The correlation between MSR and RCR was weak but highly significant (Spearman r=0.21, p<0.0001), indicating that papers with high scores for methodological standards were somewhat more likely to also score highly for regulatory standards.

This evident shift in median emergence time is highly significant (Friedman two-way ANOVA, p <.0001).

Furthermore, comparing datasets showed highly significant differences (Wilks’ lambda = 0.0119, F(40, 10687) = 592.4963, p < 0.0001), indicating distinct multivariate distributions among the datasets.

A highly significant correlation (r = 0.74, p < 0.0001) between the LAST and the short version of the Token Test indicated good external validity of the scale.

Further, the mean GCF resistin levels, before as well as after treatment across groups showed highly significant difference with P < 0.0001.

The association between obese and CRC in overlapping DMRs was highly significant as suggested by Chi square test (p < 0.0001).

There was a significant difference between farm and slaughterhouse samples, with farm samples showing higher IgG levels ( p = 0.0074) in pigs with a pleurisy score of 1, and the differences were highly significant, with p -values < 0.0001, indicating much higher IgG levels in farm samples compared to slaughterhouse samples in pigs classified with the most severe pleurisy scores of 3 and 4 ( Figure 2 ). 3.7.

The difference was highly significant statistically ( P =0.0001) [ Table 1 ].

PHQ4 score showed a highly significant association with e-cigarette use in the bivariate ( p < 0.0001) but not multiple logistic regression, possibly revealing that PHQ4 has some correlation with other variables.

Applying the aforementioned post hoc ANCOVA sensitivity analysis, the treatment effect defined by the primary outcome measure remained highly significant ( p < 0.0001).

Independent repetition of the cross confirmed this finding; statistical analysis revealed that the result is highly significant (P value <0.0001 by the Pearson’s chi-squared test).

Both main effects were highly significant: K252 ( F (1, 12) = 70.98, p < 0.0001; 42% variance) and time ( F (2, 12) = 29.83, p < 0.0001; 36% variance).

The log-rank test indicated a highly significant difference ( p < 0.0001) when the PrC-210 survival curves were compared to their respective vehicle-treated groups (i.e., fasted or fed).

Interestingly, the newly emerging glycemic marker glycated albumin showed a highly significant difference in both the groups (Group II: P= 0.0001, Group III: P<0.0001) when compared with control.

In addition, there was a highly significant negative linear correlation between the N% and C/N ( P < 0.0001, R 2 = 0.8844).

The within‐design heterogeneity is highly significant ( Q = 75.37, p < 0.0001).

= 1, 3; χ 2 = 12.50; p = 0.0058) and a highly significant generation × treatment interaction (GLMM; n = 6; d.f. = 1, 3; χ 2 = 31.75; p < 0.0001), suggesting that the effect of IMI on larval mortality varied across generations ( Figure 6 ).

On the other hand, the group of subjects who received PI vaccination showed a trend toward an increase in the median IgG titer (median values of 0.3 to 579 (P<0.0001), 0.00–401.4 (P = 0.3125), and 971.3 to 2163 (P = 0.3008) in group 1,2, and 3 respectively), except slight decrease of IgG value for Group 4 (median value of 1067 to 1021; P = 0.9717).

The reduction in Wexner score after 8 weeks of treatment when compared with baseline was highly significant for all NRL001 treatment arms ( p < 0.0001) as well as placebo.

There was a highly significant positive linear relationship between overall basal area and large tree basal area (F 1,28 = 127.5, R 2 = 0.82, P < 0.0001).

A highly significant interaction of age*genotype was found for all regions investigated ( p < 0.0001), supporting an age-dependent increase in [ 18 F]-AV45 uptake in TASTPM mice.