“a decreasing trend”

The rate of HBV infection detection from 2018 to 2021 showed a decreasing trend year by year ( P = 0.01), with the decline being most significant from 2018 to 2019 (Fig. 3 ).

Over a 48-month follow-up period, all three groups showed a decreasing trend in knee JSW, with the IACI group having the fastest JSW decline rate at -0.020 mm/month (95% CI: -0.027 to -0.013, p < 0.01).

The upward trend of blood creatinine of the rats in the DN group suggested that kidney function had changed (P<0.001), and only the PH group showed a decreasing trend (P<0.01) in ACR levels, but the intensity was lower than that in the MET group ( Figures 2B, C ). 3.5.

There was a slight increasing tendency in DDDc of Dasatinib in tertiary hospitals ( p < 0.01), and a decreasing trend in DDDc of Nilotinib in primary hospitals ( p < 0.01).

Between April 2020 and January 2021, we see a decreasing trend in the number of bacterial infections over time (estimated slope −0.06791, p value<0.01).

Similarly, there is a decreasing trend in trait anxiety with age ( p < 0.01), although this seems to increase in the age group above sixty years.

When stratified by type, there was a decreasing trend for melanoma in both men and women (males: −6.4, p = 0.01; females: −4.3, p = 0.032).

Results from the ARIMA modelling showed that at the baseline, before the pandemic, the level of monthly number of antibiotic prescriptions was 248,560 (95% CI: 224,261 to 272,856; p<0.001) and there was a decreasing trend of 1,202 in monthly number of prescriptions (95% CI: -2,107 to -262; p<0.01).

The rate of O 2 · − in oat seeds showed a decreasing trend throughout the aging process, with a highly significant difference observed between the two varieties ( P < 0.01).

Finally, the fourth class ( normative class ; 52.13% of participants) showed a slight increase in distress during the first COVID‐19 survey (on May 2020 approximately) and a decreasing trend onwards (intercept in comparison with the first class intercept, B = 2.70, Z = 11.84, p < 0.01; time effect, B = −0.01, Z = −34.45, p < 0.01).

In this subgroup, mean plasma indoxyl sulfate concentrations demonstrated a decreasing trend from the baseline value of 2.5 ± 0.7 μg/mL, with values of 2.1 ± 0.9 μg/mL at week 4 (p < 0.01), 2.1 ± 1.3 μg/mL at week 12 (p = 0.07), and 2.0 ± 1.1 μg/mL at week 24 (p < 0.05).

In the PRF, CGF, and control groups, pain had a decreasing trend ( P =0.010, P <0.001, and P =0.001); PI had a significant increasing trend ( P =0.034, P <0.001, and P <0.001); crestal bone level had a significant increasing trend ( P =0.023, P =0.033, and P <0.001); and the size of periapical lesion had a significant decreasing trend ( P =0.004, P =0.002, and P =0.048).

Diazepam and lorazepam use declined significantly over time ( p < 0.001); clonazepam showed a decreasing trend ( p = 0.01 Fig. 2 ).

From 2010 and 2020, the prevalences of birth defects were 187.28, 227.81, 204.96, 189.61, 221.87, 218.39, 182.03, 179.96, 163.14, 160.34, 164.75 per 10,000 fetuses, respectively, and showed a decreasing trend (χ 2 trend = 246.44, P < 0.01) (Table 1 ).

For the ten years of the study period (2009 to 2018), the lethality rate showed a decreasing trend of – 13.5% ( p = 0.01).

In the case of the Triton-X-treated cornea, even though a decreasing trend of cytotoxicity is observed with time, the decrease (in fold change in LDH release or decrease in cytotoxicity) with time is not statistically significant ( p > 0.01) except at 24 h, when compared to the 3 h data.

The EFS and OS for patients with stage I, II, III, and IV MGCTs showed a decreasing trend, with EFS rates of 95.27%, 93.06%, 73.63%, 70.43% ( p < 0.01) and OS rates of 100%, 93.31%, 87.69%, 84.64% ( p = 0.04), respectively.

From December 2020 to August 2021, there was again a decreasing trend (MPC, -13.8; 95% CI: -23.3, -3.5; P = 0.01), followed by a slight increase from August 2021 to April 2022 (MPC, 4.2; 95% CI: -8.4, 18.6; P = 0.52).

IL-1β expression tended to be higher at 3 dpi in Groups 2 and 3, whereas it showed a decreasing trend over time in the other groups ( p < 0.01) ( Figure 6D ).

Under the – 4 °C treatment, DsCREBBP expression remained at a decreasing trend within 6 days ( P < 0.01), whereas the decrease was highly significant by day 9 ( P < 0.01) (Fig. 3 A).

Specifically, the study observed a decreasing trend in RA volume index across the three groups: normal glucose metabolism, prediabetes, and T2DM (median values of 25.2, 22.1, and 21.7 mL/m 2 , respectively; P < 0.01).

Blood biochemical parameters ( Table 4 ) indicated a decreasing trend in BUN concentration with increasing levels of MP supplementation in broilers (P < 0.01).

The expression of ROS in the NMN-treated group showed a decreasing trend at 24 h or 48 h (120.3±15.28 24 h aged vs. 78.00±3.61 24 h aged+NMN; 167.3±5.51 48 h aged vs. 117.0±6.11 48 h aged+NMN; Fig 2B ; p<0.01; n = 3).

Post hoc tests showed a significant decrease in CLO-65 in F1 compared to CLO-0 and a decreasing trend in CLO-65 in F2 compared to CLO-0 ( P <0.01; P =0.086).

General hospitals had the highest proportion (54.8%), while tertiary general hospitals demonstrated a decreasing trend ( p <0.01).