ALFF of left BA45 was negatively correlated with age and showed a decreasing trend in the deaf group along with age increased ( r = −0.568, p = 0.005), but it showed an increased trend in the control group, though there is no significant correlation ( r = 0.171, p = 0.512) ( Figure 3 ).
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Although a decreasing trend with age was observed, the overall difference among groups was statistically significant ( p = 0.005).
After controlling for confounding factors, there was a strong evidence of a decreasing trend in care seeking with increasing distance to care ( P ≤ 0.005).
The age, smoking, as well as the levels of BMI, AHI, ODI, MAT, TSA90 and the prevalence of hypertension and COPD exhibited a decreasing trend with the elevated MSpO 2 , except for the levels of LSpO 2 and the prevalence of dyslipidemia, which showed an increasing trend (all P < 0.005).
Afterwards, a decreasing trend was observed until month 10, when a significant lower MM was found to be 12.41% lower than the peak MM at month 7 with statistically significant ( P =0.005).
Nine out of the 14 FAs showed significant differences in the relative amounts between maturity stages, where an increasing trend was found for 14:0 ( F = 20.41, p < 0.05), 20:2 ( F = 4.17, p = 0.006), 20:3n3 ( F = 3.08, p = 0.024), 20:4n6 ( F = 4.48, p = 0.004) and 20:5n3 ( F = 3.20, p = 0.028), a decreasing trend for 18:0 ( F = 4.31, p = 0.005), 18:1n9 ( F = 3.53, p = 0.013) and 20:1 ( F = 18.37, p < 0.05), and an increase for 16:0 from stages III–VI ( F = 18.18, p < 0.05), followed by a decrease at stage VII (Fig. 4 a; Additional file 1 : Table S1).
1C ), a decreasing trend in total antibiotic resistance potential was observed over time ( P < 0.005) ( Text S1 ).
Results We included 419 patients with IE, the incidence of which showed an increasing trend (relative risk 1.06, p=0.005), whereas mortality demonstrated a decreasing trend (incidence rate ratio 0.93, p=0.020).
Interestingly, however, the LRIG1 mRNA levels showed a decreasing trend ( P = 0.00547, Jonckheere-Terpstra test) with increasing tumor grade, i.e., from GS (Gleason Score) 6 to GS9 tumors (Supplementary Fig. 13a ).
The annual positive isolation rate ranged from 12.7% (2018) to 28.4% (2010), with a decreasing trend ( p = 0.0058).
The intra-laboratory %CVs presented a decreasing trend with increasing insulin concentration (ANOVA: P =0.0059; 202111 vs. 202113 P =0.0255; 202111 vs. 202115 P =0.0063); however, no distinct trend was observed for C-peptide (ANOVA: P =0.702) ( Fig. 1 ).
The time between U gait and U crit – hereafter classified as ‘time spent bursting’ (TSB) – revealed a decreasing trend with temperature ( P =0.0059), with no apparent P CO 2 effect ( P =0.8760).
Meanwhile, there was a decreasing trend in in-hospital mortality across COVID-19 waves ( p = 0.006) ( Fig. 3 B).
The mean male to female incidence rate ratio was 1.28 (95% CI = 1.26–1.30, range = 1.15–1.41), with a decreasing trend during the study period ( r = −0.47, p = 0.006; Figure 1 ).
A decreasing trend for FGIDs was observed with increasing level of education (83.7%, 66.9%, 59.3%, P value = 0.006).
Baseline demographic and clinical characteristics were well balanced between the SCDM-DHM group and the control group ( p > 0.05), with no statistically significant differences observed in terms of maternal age, birth weight, gestational age, number of males, delivery mode, SGA status, or length of hospital stay; a decreasing trend in the number of single births was observed in the SCDM-DHM group ( p = 0.006).
A decreasing trend in all CCS categories was observed among patients undergoing CABG, while in the PCI group, the trend remained stable for all CCS categories until 2009, and then it showed an increasing trend for low‐risk CCSs of 1 to 2 (APC, 3.1; P =0.006).
Our generalized estimating equations analysis revealed a decreasing trend in volume, fitting a quadratic function ( p = 0.006).
The trend of overall DBP over time was also significantly different between the groups, and a decreasing trend was observed in the RIC group (F = 3·078, P = 0·006, group-by-time interaction).
Trends relating to the total amount of methadone prescribed remained stable, but a decreasing trend in the number of prescriptions (2.4%; RR = 0.976, 95% CI 0.959–0.993, p = 0.006) and an increasing trend in the quantity prescribed per prescription (2.8%; RR = 1.028, 95% CI 1.013–1.042, p < 0.001) was observed post-lockdown.
The RR of twins for stillbirth, compared with singletons, was 3.27 overall, ranging from RR = 5.7 in 2012 to RR = 2.5 in 2021, with an upward trend in the period 1957-1988 (APC = 1.2, 95% CI: 0.7 to 1.8, p < 0.001), a stabilization during 1988-2012, and a decreasing trend in the period 2012-2021 (APC = -4.8, 95% CI: -8.0 to -1.4, p = 0.006) (Figures 7 - 9 , Tables 1 , 3 ).
In overall study subjects, mean HbA1c levels showed a decreasing trend with age from 8.2% at age 19 to 7.7% at age 22 ( P =0.007).
We saw a decreasing trend, from 20.7% of patients in 2010 to 8.9% of patients in 2019 ( p = 0.007, Mann–Kendall trend test; Figure 2 ).
As for breast cancer, a stable trend (AAPC: 0.3%, 95% CI − 0.3 to 0.9%, P = 0.28) was observed in rural areas compared to a decreasing trend (AAPC: − 2.7%, 95% CI − 4.6 to − 0.7%, P = 0.007) in urban areas.
The paired t-test analysis of levels CRP during the first three weeks of hospitalization showed a decreasing trend in CRP levels during hospitalization ( Fig 3 ), with a significant decrease in CRP levels in the first week compared to the third week (P = 0.007). 4.