Barely Significant
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“a decreasing trend”

47,181 sentences · 47,181 papers · 78,848 search hits before verification · confirmed specimen

Sighted at

p=0.09

Listed by Hankins (2013) · Otte et al. (2022)

In the literature

In a study examining the effect of ZA on bone microarchitecture in male participants with non-metastatic prostate cancer undergoing androgen deprivation therapy, there was no significant improvement in bone microarchitecture in the ZA arm despite an increase in BMD.[ 27 ] This phenomenon can be explained by the failure of ZA to completely suppress imbalanced bone remodelling, together with its inability to penetrate and distribute in sufficient quantity into deeper cortical bone tissue.[ 27 ] Effect of ZA on BTMs β-CTX levels showed a decreasing trend in the ZA arm (median percentage decrease of 43.22 at 12 months), while in the placebo arm, they initially decreased at 6 months (median percentage decrease of 10.3) but showed an increasing trend at 12 months (median percentage increase of 10.47).
In terms of lymph node yield, despite a decreasing trend, the average number of nodes resected in surgery during both learning and postlearning phases was considerably higher than the recommended threshold values of 15 nodes [mean (SD): 36.8 (16.1) vs. 29.1 (10.3), P <0.001].
Compared with baseline (Table 1 ), there was a significant decrease in mPAP at months 6 and 18 (mean difference; -2.72 at month 6; P = 0.022, -2.56 at month 18; P = 0.030), and a decreasing trend at month 12 although no significant difference was noted (mean difference; -3.18; P = 0.063; R = 0.58).