Conclusion Cadonilimab + TKI showed a favorable trend in safety and efficacy, especially when applied as first-line systemic therapy for uHCC.
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“a favorable trend”
Sighted at
p=0.09
In the literature
Nevertheless, anti-PD-1 immunotherapy plus chemoradiation is associated with a favorable trend toward improved PFS versus standard therapy in patients with locally advanced HNC.
However, patients receiving LR showed a favorable trend in 2-year DFS (HR=1.40, 95% CI: 1.16–1.69) and 5-year DFS (HR=1.37; 95% CI: 1.05–1.77), although these results are not conclusive due to underpowered significance.
Plasma triglyceride levels were significantly elevated in the inulin‐only group but showed a favorable trend in both EA‐treated groups (Figure 4e ).
This might suggest a favorable trend compared with prior studies on this topic, although they are not directly comparable due to different patient populations.
For patients with diabetes mellitus, our analysis suggests a favorable trend concerning the effect of 25(OH)D on eGFR and UACR without significant differences.
Image-based NIRAF assistance significantly outperformed the standard naked-eye technique in several outcomes, or showed a favorable trend.
The observed reduction in mortality in more recent cohorts treated with dedicated devices suggests a favorable trend over time.
Additionally, a descriptive analysis of OS indicated a favorable trend in both the PD-L1-positive and intention-to-treat (ITT) populations.
PFS showed a favorable trend but was not statistically significant (HR=0.69, 95% CI 0.42–1.14, p=0.15).
The median RFS was 21.7 months in the CY+ group and 30.6 months in the CY− group, showing a favorable trend in the CY− group but no statistically significant difference ( p = 0.357) (Figure 2A ).
Additionally, in the 4-week group, adjunctive perospirone demonstrated a favorable trend compared to placebo across multiple measures, including improvements in MADRS, HAMA, QIDS-SR16, and Q-LES-Q-SF scores, though the magnitude of changes was smaller than that in the 4-to-8-week group ( Supplementary Tables S17–S19 ).
Cefiderocol is well-tolerated and associated with a favorable trend toward improved overall survival [ 9 ].
Conclusions Patients submitted to endomanometric LNF showed a favorable trend toward better symptoms control, decreased postoperative complications, better satisfaction, and higher PPI discontinuation compared with those who underwent LNF alone.
A similar trend was observed for HrQOL, as in multivariate analysis, there was no significant effect of antipsychotics on proxy HrQOL (OR: 0.46 [CI95%: 0.13–1.55], p = 0.210) and a favorable trend for self-reported HrQOL (OR: 3.58 [CI95%: 0.94–13.67]).
20 Nonetheless in a recent study on young subjects in the United States between 1988 and 1994 and between 2007 and 2010, a favorable trend in serum lipid concentrations was observed. 21 A study on children aged between 10 and 11 years in South Korea reported that the mean levels of TC were 166 mg/dL in the girls and 168 mg/dL in the boys, the mean levels of LDL-C were 96 mg/dL in the girls and 99 mg/dL in the boys, the mean levels of
47 In this study, the survival rate was not significantly different between the LS-MF and HS-MF groups, although there was a favorable trend in the HS-ER group compared with the HS-MF group, indicating the need for further studies with increased power.
While not achieving statistical significance, the data exhibited a favorable trend toward improved outcomes.
No increased incidence of adverse events was observed ( p > 0.05). Conclusions: This study demonstrated that a single dose of alirocumab in STEMI patients undergoing PPCI was associated with significant improvement in LDL-C levels, attenuation of early postoperative inflammation, and a favorable trend toward improved cardiac function and quality of life, while maintaining an acceptable safety profile.
Despite a favorable trend, the benefit of postoperative chemotherapy on overall survival has not been shown to be significant.
The fact that more than half of the dentists polled are aware of teledentistry, with a sizable proportion actively practicing it, indicates a favorable trend.
It is worthy of attention that the Gb between the Central and Western regions progressively drew closer to that between the Eastern and Central regions, which indicates a favorable trend of CDL between the two regions.
There was also a favorable trend in overall survival in the GS combination group, but still no statistical significance ( p = 0.517).
Conclusions In patients with moderate-to-severe TR at baseline, LBBAP was associated with a significant reduction in TR severity, together with improved left ventricular function and a favorable trend in pulmonary pressures.
This finding indicates a favorable trend in China’s advancement of the SDGs, underscoring robust synergies across multiple goals.