The high prevalence of ESBL production (57.3%) among our isolates, which exceeds the 43.5% national average reported in a 2018 meta-analysis [ 28 ], underscores a worrying trend of escalating resistance to cephalosporins in Tehran’s hospitals.
The universal presence of fosA highlights a worrying trend, as fosfomycin is often recommended for UTI treatment in Africa.
These figures reflect a worrying trend when compared with global population estimates, such as those of Guthold et al.
Both 11–14 and 15–17 year-olds logged multiple energy drink ads, a worrying trend given the established health risks of these products during adolescence ( 54 ).
The nutritional status (according to MNA scores) improved in the first 10 years in the whole sample and in nursing home residents, but a worrying trend suggesting a worsening nutritional status was seen in the last five years.
What are the long-term impacts for the United States and the world?" This query calls to mind a worrying trend of political interference in research and the provision of funding as leverage against savings and national policies.
The rise in overweight and obesity levels worldwide is a worrying trend ( 1 ) ; it is expected that in 2025 nearly one out of four children lives with overweight or obesity ( 2 ) .
Despite numerous stewardship efforts, antibiotic consumption remains high in both medicines, thus fueling a worrying trend: the latest estimates suggest that, in the absence of effective interventions, AMR could claim up to 10 million lives annually by 2050 [ 4 ].
In particular, the DSNs highlighted a worrying trend in digital healthcare being imposed from the top down, which has led some healthcare units to transition to only provide digital diabetes care.
Over the past decade, US osteoporosis treatment rates have dropped from 15 to 8%, a worrying trend that is worse among patients with diabetes [ 27 ].
A significant portion of the bacterial strains studied exhibited resistance to six–eight antibiotics, reflecting a worrying trend towards multidrug resistance.
As in studies in our country, colistin generally remained the most active agent [ 107 ], colistin resistance showed substantial variability and a worrying trend of increase over time, reaching up to 60% in Greece [ 97 , 108 , 110 ].
2 However, research has consistently indicated a worrying trend: empathy levels among healthcare students, including those in dentistry, often decline as they progress through their academic and clinical training. 19 , 22 This decline is often attributed to various stressors inherent in medical and dental curricula, such as intense clinical experience, rigoro
Similarly, total deaths are expected to rise from 1,535 in 2024 to 2,467 by 2033 (60.7% increase), marking a worrying trend of more severe disease outcomes ( Figure 6 ).
Although incidence rates have declined in many high-income countries, a worrying trend has emerged in younger populations, where both prevalence and incidence are increasing [ 2 , 3 , 4 ].
However, in the past decades, there has been a worrying trend of increased antibiotic misuse [ 2 , 3 ].
However, there is a worrying trend of non-obese and lean individuals with normal body mass index (<25) exhibiting characteristics of liver disease ( Leung et al., 2017 ).
[ 1 ] However, recent epidemiological data reveal a worrying trend toward younger populations.
In addition, it serves as a tool to encourage research, certify the skills acquired at the university, and contribute to the scientific knowledge that the institution shares with the community through its publication.[ 1 ] However, Peru has reported a worrying trend in the fields of psychology and medicine.
Despite persistent majority support, however, there is a worrying trend of declining support according to recent opinion polls, and the jostling of environment versus other policy priorities 31 , 33 .
However, a worrying trend was evident: delay in reconstructive surgery was associated with an increase in the severity of nasality.
Our findings indicate a worrying trend in the rising mortality rates associated with liver cancer, particularly in high and high-middle socio-demographic index (SDI) countries.
These findings were reinforced by the observational insights from Ramjan et al., who highlighted a worrying trend: students increasingly favour digital contact over in-person communication, a behaviour that may erode essential professional skills [ 35 ].
This is a worrying trend that affects all quintiles of the Socio-demographic Index, with the lower quintiles showing the largest percentage increases. 1 Over the next 10 years, it is anticipated that low- and middle-income nations will account for more than 75% of cancer-related deaths. 2 Cancer demands a multifaceted approach to effective management.
Impact of the Financialisation, Corporatisation and Commodification of Healthcare on Its Accessibility and Quality Currently, there is a worrying trend of increasing transition of public healthcare services into private ownership (European Network of Corporate Observatories 2021 ; Marchandot and Morel 2025 ; Suzuki et al. 2025 ).