“a worrying trend”

The high prevalence of MDR strains, particularly against Third-generation cephalosporins and Fluoroquinolones, reflects a worrying trend consistent with regional and continental data.

This metabolic disorder demonstrates a worrying trend of increasing incidence among younger individuals and serves as a major risk factor for various chronic conditions, including hypertension, fatty liver disease, cirrhosis, peripheral vascular diseases, ischemic cerebrovascular diseases, and pancreatitis ( 216 , 217 ).

Ceftriaxone, Ciprofloxacin, and Colistin showed a comparatively high non-susceptibility signal in the pooled data, highlighting a worrying trend toward reduced effectiveness of third-generation cephalosporins and certain last-resort agents like colistin.

Although this is not unique to Sierra Leone, it reflects a worrying trend in the cascade since more than 20% of those who tested positive still left the cascade.

Moreover, this study discloses a worrying trend of inconsistent adherence to antibiotic guidelines, irrespective of changing levels of healthcare access and awareness.

Especially very high intake of total SSBs, attributed to over 32% of total daily beverage consumption may be a worrying trend, when comparing it with the results of the analysis of the database of SSBs intake for children and adolescents aged 3–19 years from 185 countries with the result of 23% [ 19 ].

Recent epidemiological data indicates a worrying trend; a 2024 cross-temporal meta-analysis revealed that the prevalence of Smartphone addiction among college students has been steadily climbing over the past decade, exacerbated by the digitalization of education post-pandemic ( Billieux et al., 2015 ).

In addition, factors such as misinformation, socioeconomic conditions, and failures in health infrastructure contribute to greater vaccine hesitancy, following a worrying trend observed globally.

This is a worrying trend because the Ministry of Health Uganda advises HIV-positive mothers to breastfeed their infants exclusively for the first six months of life and to continue nursing for at least another 12 months while supplementing their diets.

The consistent sentiment among midwives that they are unfairly singled out for blame is a worrying trend that must be addressed to ensure a fair and balanced approach to audits.

Although the absolute number of deaths does remain low, these numbers point to a worrying trend.

Traditionally viewed as a problem affecting older adolescents and adults, recent epidemiological data highlight a worrying trend in which drug abuse, including prescription medication abuse and illicit substance use, has extended into younger school-aged children.

3.1.1.2 Academic concealment and peer assault A worrying trend is emerging in the academic environment of graduate nursing students: academic secrecy and zero communication with each other.

Introduction Stenotrophomonas maltophilia has emerged as an important opportunistic pathogen on a global scale, with a worrying trend toward multidrug resistance ( Trifonova and Strateva, 2019 ; Brooke, 2021 ).

The study highlights a worrying trend toward a sedentary lifestyle and excessive food consumption, which is potentially intensified by a decrease in physical activity and poor dietary regulation.

Although complete resistance to glycopeptides remains uncommon, the emergence of vancomycin-intermediate strains reported from southern India signals a worrying trend[ 51 ].

According to the latest data, overweight and obesity in adults and children are showing a worrying trend worldwide, with 45.1% of the population being overweight or obese.

However, in the two longitudinal studies identified, there was a worrying trend of declining attitudes towards communication as students progressed through their training, particularly in the clinical setting ( Givron & Desseilles, 2021 ; Rosenbaum, 2017 ).

A study conducted in Nigeria among health care workers found that approximately 85% believed all children with sore throat should be treated with antibiotics. 5 Furthermore, a study conducted among the general population in Saudi Arabia found nearly half of the participants believed antibiotics are helpful in treating sore throat. 15 While this shows basic awareness that bacterial infections require antibiotics, it also portrays a worrying trend of overprescription or self-medication especially in places where use of antibiotics is readily accessible over the counter, 19 which in turn can lead to the rise of resistant bacterial pathogens. 20 Addressing this issue requires joint efforts, particularly from governments and policy makers.

Amphibians are also the most threatened among terrestrial vertebrates, with a worrying trend of increased risk of extinction for newly discovered species, due to restricted ranges, small population sizes and impact from human activities 7 .

Recent research from the United States highlights a worrying trend: a noticeable proportion of youth have experimented with ONPs, and a subset continues to use them regularly [ 8 , 9 ].

10 Current data reveal a worrying trend where eligible populations either delay or refuse the HPV vaccine, driven by factors such as lack of confidence in vaccine safety and efficacy, misinformation and inadequate healthcare recommendations. 11 , 12 Parental consent and acceptance are essential before administration because the targeted

Prevalence of psychological distress The observed prevalence of depressive symptoms (33.51%) and anxiety symptoms (10.07%) reflects a worrying trend among healthcare-related students.

Empathy is widely regarded as a teachable professional skill, yet evidence consistently shows a worrying trend: medical students’ empathy tends to decline during their education [ 3 ].

In the present work the prevalence of MF resistance was 62%, indicating a worrying trend.