Barely Significant
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“an increasing trend”

63,972 sentences · 63,972 papers · 107,686 search hits before verification · confirmed specimen

Sighted at

p<0.09

Listed by Hankins (2013) · Otte et al. (2022)

In the literature

Bortezomib was felt to be safe and the authors suggested addition of bortezomib in patients with high antibody titers (≥ 1:51,200) at or beyond 6 months on enzyme replacement therapy and/or when an increasing trend or persistence of antibody titers is associated with clinical decline.
20 In addition, Swedish researchers have utilized the Swedish Spine Register to demonstrate an increasing trend in surgical lumbar spine interventions over our years of interest, which suggests that the economic downturn may not have affected spinal procedures within Sweden as well. 21 The incidence of elective lumbar spine surgery relative to the employed population increased during the economic downturn from 2008 to 2009 (4.9%).
The initial guidelines by the IOM in 1930 recommended that pregnant women should gain 6.8 kg irrespective of weight status.[ 19 ] Subsequently, with increasing prevalence of obesity and an increasing trend in birth of macrosomic infants, these guidelines were revised in 1990 and 2009.[ 9 , 20 ] With overweight and obesity significantly contributing to the growing prevalence of large for gestational age infants and increasing the risk of pregnancy-related complications,[ 21 ] the IOM published new guidelines in 2009.[ 9 ] This new recommendation was based on WHO BMI categories and included a more restrictive range for weight gain for obese women.