“approaching, but not reaching, significance”

A random effects model was used to examine the repeated measurements of FEV 1 according to study day; the analysis found a significant difference in slope parameter between the control and CC-11050 groups, and a difference approaching, but not reaching, significance for everolimus ( appendix p 28 ).

The limited sample size in the shoulder subgroup (n = 5) may have contributed to the result approaching, but not reaching, significance.

Finally, the relatively modest sample size of athletes in this study may have limited statistical power, contributing to several effects approaching, but not reaching, significance.