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extremely significantp < 0.00010.0× alphaqualified
Subsequently, at post-intervention (TF3) and the fifth cycle (FF1), it decreased to 67.70 ± 22.37 and 70.51 ± 33.23, respectively, demonstrating a statistically extremely significant reduction from the baseline ( p < 0.0001).
extremely significantp <0.00010.0× alphaqualified
In particular, compared with the level observed at 0 d (CK), the expression of pyrB (5-fold), flmH (8-fold), pilR (4-fold) and bopD (5-fold) reached extremely significant levels at 15 days (t=20.51, df=4, p <0.0001), 10 days (t=14.28, df=4, p <0.0001), 5 days (t=26.79, df=4, p <0.0001) and 10 days (t=32.57, df=4, p <0.0001), respectively ( Figure 6C ).
extremely significantP < 0.00010.0× alphaqualified
P values are calculated using unpaired t tests with Welch’s correction, and the levels of statistical significance are assigned as follows: P ≥ 0.05, not significant (n.s.); 0.01 ≤ P < 0.05, significant (*); 0.001≤ P < 0.01, very significant (**); P 0.0001 ≤ P < 0.001, extremely significant (***); P < 0.0001, extremely significant (****).
extremely significantP < .00010.0× alphaqualified
Comparison of the Puncture Depth Between the Ipsilateral Ventricle and the Contralateral Ventricle The difference in the puncture depth between the ipsilateral ventricle and the contralateral ventricle was extremely significant ( P < .0001); the depth of puncture to the ipsilateral ventricle in 373 patients was less than 60 mm, and the depth of puncture to the contralateral ventricle in 37 patients ranged from 52 to 65 mm (Figure 4 D).