“highly significant”

The mean fluorescence intensity for targeting liposome was about 1.41, 2.74, and 5.72-fold stronger than that for DOX/CEL lipo, DOX lipo, and DOX solu respectively after 4 h incubation, showing a highly significant difference (P<0.001).

Secondary efficacy outcomes Three secondary efficacy outcomes were assessed, and in comparison, any dose of eptinezumab had a highly significant efficacy, ≥75% migraine responder rate [RR = 1. 80, 95% confidence interval (CI): 1.40, 2.33, P < 0.001 Figure 2 b], ≥50% migraine responder rate [RR = 1.46, 95% CI: 1.33, 1.61, P < 0.001 Figure 2 c], and 100% migraine responder rate [RR = 2.41, 95% CI: 1.08, 5.38, P = 0.03 Figure 2 d].

The monthly difference in breast cancer cases showed a highly significant negative linear correlation with monthly new COVID-19 cases (r=0.79, p<0.001) ( Figure 2 ).

For example, using the 36 breeds in each of the three databases (the ALL THREE dataset), the pairwise correlations in breed cancer mortality were highly significant (US/UK r = 0.741; US/FINN r = 0.590; UK/FINN r = 0.744; d.f. = 34, all p < 0.001).

Bartlett's test was highly significant ( p < 0.001) and the Kaiser–Meyer–Olkin measure value of 0.77 supported the factorability of the matrix.

With these two correlated samples, the change of attitude in pre and post assessment was highly significant (P<0.001).

Our study results were consistence with above said study, the neck circumference was found highly significant with difference of (p < 0.001).

The results showed that the main effect of “group” was highly significant, F (2, 139) = 9.075, p < 0.001, η p 2 = 0.115 (90% CI [0.039, 0.194]), with clear increases in CG and EG2 cont as well as decreases in EG1 disc .

After adjusting for covariates, the regression analysis showed a highly significant association (p value< 0.001) between unemployment and psychological distress (OR=1.55; 95% CI 1.03, 2.31), and alcohol consumption (OR=0.67; 95% CI 0.48, 0.92).

The differences were highly significant (p < 0.001) ( Table 1 , Table 2 ).

Regarding the type of occupation, compared to other occupation categories, the majority of study participants were government employees (30.31%) and students (27.87%), and they had a highly significant association ( p < 0.001) with dread.

The wild-type virus was highly sensitive to heat treatment and showed a highly significant ( P < 0.001 or P < 0.0001) decrease in antibody responses after heat treatment both by ELISA at 21 and 28 days postvaccination (dpv) and VNT ( Fig. 4 ).

The linear regression between water and logger temperature (20 points) was highly significant ( R 2 = 0.99, p = 0.001).

Pearson’s correlation coefficient reveals a highly significant strong negative correlation between deployment and finishing time considering the past 25 years (r < −0.940, p < 0.001).

The genotype and phenotype effects were highly significant ( P = 0.001 and P = 0.004), explaining 35 and 9% of the overall variation in gene expression ( Table 2 ).

p < 0.05 (*) was considered statistically significant, p < 0.01 (**) highly significant and p < 0.001 (***) extremely significant.

Regarding the main interaction effect at T3 (see Table 3 ), the GAD-7 measure was highly significant ( t = −4.52, p < .001) across all imputations (see OSM 4).

As far as length of stay is concerned, patients were divided into three groups, depending on whether the length of stay lasted 7 days or less (144 patients; group A), between 8 and 14 days (412 patients; group B) or more than 14 days (221 patients; group C); a highly significant difference in the probability of readmission was found ( p < 0.001; Fig. 2 b).

The A549 cell monolayer treated with temporin-SHf showed a highly significant reduction of scratch healing (wound closure) ( p < 0.001; Fig. 10 a, b), indicating that the temporin-SHf treatment prevents cancer cell migration.

The full multiple regression model of main and interaction terms showed a highly significant intercept ( p < 0.001), significance for the higher vaccination numbers as compared to vaccination 3 but no significant effect of the days post vaccination nor any of the interaction terms.

A statistical analysis of the LEC values for the two assays was conducted including all test runs with concordant results (paired sample t -test) and resulted in a highly significant difference ( p < 0.001).

By the end of the study (Day 42) the decrease in PI-NRS scores for the IP group was maximal (↓61.32%) and highly significant ( p <0.001) in comparison to the placebo group (↑2.47%).

The biochar amendment exhibited highly significant positive effects on multifunctionality ( P < 0.001), whereas the changes in ecosystem multifunctionality had negative associations with the average of the indicators of soil biodiversity ( P < 0.05) ( Supplementary Figure 4 ).

There was a highly significant ( p < 0.001) enhancement in the BF permeation from BF-NLCs-opt and BF-NLCsopt gel than BF gel.

Regarding the CSF‐T classification, the higher CSF p‐tau181 concentration in AD dementia (32.3 [26.5;47.5] pg/mL) as compared to the MCI (24.8 [18.8;36.0] pg/mL) and CN (19.8 [14.9;26.6] pg/mL) was highly significant ( p < 0.001; Figure 1B ).