“highly significant”

We found the correlation of similarity within days and across days to be high (ρ = 0.75) and highly significant (P<10 −50 ).

However, even though the overlap between the two target sets was modest (46%), it was statistically highly significant ( p <10 −50 ).

The Spearman correlation coefficients (ρ) were 0.83 for both the nonstimulated and EGF-stimulated conditions, with highly significant p -values <1 × 10 –50 .

The RNA-seq based estimates of the change in transcript abundance showed a highly significant positive correlation with the change in the long/short-ratio ( Fig 2B ; correlation coefficient 0.32; p-value <1.0E-50), which was even stronger for the 97 genes with significant tail-length change after multiple-testing correction ( Fig 2B ; correlation coefficient 0.4; p-value = 4.4E−05), suggesting that changing the poly(A)-tail length due to reduced PAPS1 activity alters transcript abundance.

Relationship of citation source to citation validity Pearson’s chi-square tests revealed a highly significant association between citation source type (article vs. book) and citation validity across all three models (χ2 ≥ 236, df = 3, Bonferroni-adjusted p < 1 × 10 − 50).

A minority of SNPs > 500 kb away from their associated eGenes were highly significant (0.5%, P < 1 × 10 -50 , 13.4% with P < 5e-8) (Figure 4 A).

In contrast, NLR showed a moderate correlation (r = 0.6299) with a highly significant difference between the pre- and post-deployment values ( p = 1.43 × 10 −50 ) ( Table 3 ).

As a group, haplotype-specific FIRE scores for these 124 peaks carried highly significant differences between their corresponding haplotypes (paired t test, p < 2 × 10 −50 , Figure 4 D).

This overlap is highly significant ( P = 6 × 10 -50 ) and substantially greater than with any other signatures we tested (Table 1 ).

Comparing the inferred “age/maturity” of the individual B-cell cluster showed highly significant differences between the three nonmature B-cell subpopulations (Kruskal-Wallis test, p =9.84e-50).

For example, of 596 genes in cluster 6A ( Figure 6 ) ( R 2 =0.505), 165 were involved in the process of worm growth according the Gene Ontology annotations, representing a highly significant enrichment of gene function in this cluster ( P < 10 −49 ) (Supplementary Data).

Finally, the region of residence presented a highly significant association ( p < 10 −49 ), with a minimum expected value of 21,573, indicating a strong relationship between the place of residence and the distribution of maternal and late deaths, as shown in Table 3 .

This difference was highly significant ( P = 4.3E-49 in chi-square test; Supplementary Dataset S1).

These differences were highly significant across all immune parameters (Kruskal-Wallis P < 10 − 48 for all comparisons).

Consistent with our prior publications 14 , 15 , we found clear suppression of EWS::FLI1 induced targets that was highly significant at the TES with both LCE ( P = 1.1e-48) and HCE ( P = 1.5e-33)(Fig. 3b ).

The model exhibited excellent discriminative power with a C-index of 0.901, and highly significant statistical results ( p = 1.207 × 10 −48 ).

The UCP2–CD68 association remained highly significant after adjustment (partial ρ = 0.524, p = 1.80 × 10 − 48 ), confirming that the relationship between UCP2 expression and macrophage infiltration is not a spurious consequence of tumour purity variation ( Supplementary Fig.

The association between α 5 and phalloidin staining was highly significant ( P = 3.32 × 10 −48 ) ( Figure 1(c) , Table 1 ).

In addition, allele frequencies derived from the pooled sequencing experiment were compared to those derived from all individuals in the phase II genotype data and revealed a highly significant correlation (r = 0.971, p < 6.58x10 −48 ), further supporting the validity of the pooled sequencing approach.

When restricted to the 3,137 EUR cases with a PheCode probability >0.80 and their 12,548 matched controls, the 90-SNP weighted PRS was highly significant (odds ratio [OR] = 1.82 [95% confidence interval: 1.68–1.97]; p = 8.0 x 10 −48 ).

As it turned out, there is a highly significant association between induction in both systems (Fisher’s exact test p value = 1.3, 10–47).

A statistical comparison using Cochran's Q test revealed highly significant differences among the models (Q = 235.5, df = 7, p = 3.27E-47).

This 2.76-fold enrichment in this case is highly significant, with a Fisher exact test p = 8.20 × 10 −47 .

With a global average of 52.7% ± 0.12% history-congruent trials, we found a small but highly significant perceptual bias towards preceding experiences ( β = 16.18 ± 1.07, T(1.09×10 3 ) = 15.07, p = 10 −46 ; Fig 2A ) that was largely consistent across studies ( S1B Fig ) and more pronounced in participants who were less sensitive to external sensory information ( S1C Fig ).

The libraries M19 and M25 have 0,985 as correlation coefficient and have a highly significant regression (P = 2,31 × 10 -46 , after Bonferroni correction P = 7,49 × 10 -43 ).