Results Preheated, Buffered, and conventional 2% lignocaine showed statistically significant reduction in intraoperative pain ( P < 0.001) compared to pre-operative but on inter-group comparison preheated and buffered showed highly significant pain reduction compared with conventional 2% lignocaine ( P < 0.001).
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Comparison between the baseline and the ninth month was found to be highly significant ( P = 0.001), suggesting that the mouth rinse has better results when used for a longer duration of time.
Mean SAS-SV scores differed substantially between these two stratified groups and the comparison was highly significant (t (262) = -19.97, p < .001).
The analyses of both MoCA and QoL-AD scores yielded a highly significant interaction [MoCA: F (1,58) = 57.18, p <0.001, η p 2 = 0.50; QoL-AD: F (1,58) = 17.17, p <0.001, η p 2 = 0.23].
Associations around balance and body pain were highly significant between fallers and non‐fallers (OR = 4.45, 95% CI [2.10, 9.40], z = 3.91, p = 0.001 and OR = 3.51, 95% CI [1.88, 6.55], z = 3.94, p = 0.001, respectively).
Results Trait analysis Effects of years and locations were highly significant ( p < 0.001) for all traits evaluated in multiple locations (data not shown).
On the other hand, IA-AgNPs showed significantly more cytotoxic effects on cancer cells at a higher dose of 1.5 μg mL −1 , exhibiting highly significant cytotoxicity ( p < 0.001).
The results demonstrated a highly significant difference ( P < .001) in the HD duration between well-nourished and malnutrition participants (3.4 yr vs 7.9 yr, respectively).
The increase in titer from week 2 to week 12 was highly significant ( P <0.001).
The only pathogen within these species is Clostridium botulinum for which however there are two groups of points biasing the regression estimate (Additional file 3 ); even by including this species the result is still highly significant ( p =0.001).
All of the highly significant metabolic effects (p ≤ 0.001) caused by at least one concentration of selected mycotoxins are discussed in the text and visualized as bar graphs in Fig. 2 .
Highly significant correlations also occurred between MT protein and MT-2 transcript (not shown) in both the liver ( p < 0.001, r = 0.924) and kidney ( p < 0.001, r = 0.883).
A highly significant association was observed when comparing measurements across all strains ( p <0.001) and there was no correlation with weight and CCT, as these were eliminated as potential covariates.
In comparison, the majority of the lines expressing ΔN ZmL (2 lines) or any of the chimeric DGAT1s (2–4 lines identified from each construct) had highly significant ( P < 0.001) increases in lipid levels compared to both wild type and their respective null siblings ( Table 2 and Supplementary Tables 4 , 5 ).
The difference of 1.2 standard deviations between liberals and conservatives is highly significant (p < 0.001, Wald test).
Statistical significance was denoted as follows: * P < 0.05 (significant), ** P < 0.01 (highly significant), and *** P < 0.001 (extremely significant).
Lambda was found to be high and highly significant (λ > 0.6; p < 0.001) for all traits.
The difference in diploid and aneuploid DNA pattern (the ploidy state) between group 1 and group 2A or group 2B and between group 2A and group 2B and the hyperdiploid aneuploidy and the tumorigenesis was statistically highly significant ( p = 0.001).
This difference in response between the two species was reflected in the P-application rate × species interaction being highly significant (two-way ANOVA, F 3, 24 = 9.34, P < 0.001), but the main effect of P application being non-significant (two-way ANOVA, F 3, 24 = 1.91, P = 0.154).
The association between spiritual leadership and psychological capital is a strong, positive, and highly significant correlation (R-value = 0.63, P = 0.001).
The areas identified as hotspots of productivity also received a disproportionately high number of identified immigrants, with 45 of 65 individuals from 19 litters where a source of dispersal was identified, and that were of dispersal age (>5 months) being captured here, and 57 % of dispersal movements (>4 km) ending in these areas, despite them only representing 40 % of the total waterways, a highly significant difference from null expectation (χ 2 = 11.1, df = 1, p < 0.001).
The Kaiser–Meyer–Olkin (KMO) measure of sampling adequacy was 0.88, indicating meritorious sampling adequacy, and Bartlett’s test of sphericity was highly significant [ χ 2 (703) = 9,173, p < 0.001], confirming that the correlation matrix was appropriate for factor extraction.
A case-control study of Rutter et al [ 34 ] included 68 patients with a colorectal neoplasia matched with 136 controls without a neoplasia revealed a highly significant correlation between the histological severity of inflammation and the risk of neoplasia development (OR 4.69, 95%CI: 2.10-10.48, P < 0.001).
To aid in interpretation of hazard ratios we scaled selected variables either by fixed factors or to a proportion of the sample median before modeling, as some features showed highly significant associations ( p > 0.001) but HRs and confidence interval limits of nearly 1.00.
Molecular targets with highly significant ( p < 0.001) differences are given in the Supplements, Figure S2 .