“indicative significance”

Corresponding to it, TBK1 inhibitors can alleviate PA-mediated lipid accumulation, inflammatory reaction and adipocyte apoptosis in hepatocytes ( Zhou et al., 2020b ), indicating the vital indicative significance of TBK1 in the progression of NAFLD.

Statistical significance of between‐arm comparisons cannot be determined directly from within‐subject meta‐analyses, but indicative significance can be estimated by comparing instances where 95% confidence intervals for each comparison do not overlap with others. 3.5.2.

Soil physicochemical properties and mineral elements significantly affected the differential accumulation of metabolites, among which soil Sr element and organic matter exhibited crucial indicative significance for metabolic variation of rice in adjacent regions.

Therefore, the results of this mediation analysis only have indicative significance and cannot verify the causal mechanism; future prospective cohort studies or randomized controlled trials are needed for further verification. 6.

Indicative Significance of PM 2.5 and PM 10 Response Differences A key finding of this study is the marked divergence in how PM 2.5 and PM 10 respond to meteorological factors, reflecting their distinct sources, size distributions, and physicochemical properties.

This is because microbial biomarkers are often based on specific fermentation patterns or relatively stable microbial community structures, and in the non-fermentor-driven fermentation dynamic environment, it is difficult to accurately capture markers with real indicative significance, and the dynamic changes of microbial communities represented by these markers become elusive, which can easily lead to mislead the subsequent analysis and conclusion derivation.

Tumor purity of different cancer patients presented sharply different indicative significance, seemingly highlighting the potential differences in the pattern of tumorigenesis and progression of different tumors.

The aim of this study is to deeply explore the impact of oil shale thermal maturity on the organic functional group composition and carbon structure of kerogen, systematically analyze the chemical transformation mechanisms of kerogen during the thermal maturity process [ 35 ], and assess the indicative significance of these changes for the geological characteristics of the host rocks.

These results have good indicative significance for the medium and long-term forecasting of strong earthquake activity sites.

23 Thus, we should pay attention to distinguish iatrogenic diffusion especially the SM-GIST near the surgical scar, as these two metastatic patterns have different clinical and indicative significance.

In particular, parameters loading strongly on F1 predominantly reflect thermal maturity, whereas those associated with F2 are mainly related to the organic matter type. On this basis, the indicative significance of factors F1–F4 is interpreted sequentially below, providing a coherent framework for constructing a comprehensive oil-source discrimination scheme.

Furthermore, serum lipid levels may have potential indicative significance in the pathogenesis and risk stratification of APL patients, suggesting that the PTK2 gene could become a new therapeutic target, providing a new perspective for understanding the pathogenesis of APL.

Meanwhile, researchers also found that regulatory B cells have clinical indicative significance in AML [ 46 , 47 ].

Thus, HSP27 expression has a certain indicative significance in determining the malignant potentials and differentiation levels of tumors [ 24 ].

The lack of typical symptoms at early stage, biomarkers with indicative significance for early screening and markers predicting the efficacy of various treatment strategies, and early cancer metastasis have significantly contributed to the dismal prognosis of these patients.

In contrast, while the 0–4 year-old infants and toddlers and the over-50 middle-aged and elderly groups account for a smaller proportion of total cases, their infection patterns have important indicative significance.

Indicative Significance of Pyrite Type to Organic Matter Type Previous research has confirmed that framboidal pyrite is mainly developed in organic-rich shale with better organic matter types, but the potential correspondence between other pyrite and organic matter types is unknown. 49 The results of kerogen TI and the ob

The expression levels of IL-1β and TNF-α genes in animal bodies have similar indicative significance; upon up-regulating by a large margin, it indicates the occurrence of inflammatory reaction, and a small upward adjustment can indicate that the animal is in a high level of immune preparation [ 33 ].

The morphological characteristics, decorative characteristics and vessel type characteristics have certain indicative significance for dynasty identification.

Clinical features such as bilateral nasal polyps, severe olfactory dysfunction, and comorbid asthma and allergic rhinitis, as well as radiological features on Computed tomography (CT) and laboratory findings like elevated peripheral blood eosinophils and serum total IgE(tIgE), all have certain indicative significance for T2 inflammation in CRSwNP. 4 Japan's JESREC scoring system ultimately incorporated 3 indicators: CT findings, bilateral nasal polyps, and peripheral blood eosinophil counts. 5 A study by Zhang Luo's team, which included multiple indicators such as CT, peripheral blood, fractional exhaled nitric

We should identify the main species of phytoplankton as much as possible, especially those with indicative significance for the classification of trophic types, and identify at least the genus level.

Some other inflammatory biomarkers, such as CRP ≥ 16.5 mg/L [ 98 ], ESR ≥ 32.5 IU/L [ 99 ] and 35 α-hydroxybutyrate dehydrogenase (HBDH) ≥ 259.5 IU/L [ 99 ] also have indicative significance for RMPP in children.

Conclusion In conclusion, our findings stress the considerable predictive value of PIV, PLR, LMR, NLR, and NPR in assessing the prognosis of HCC patients undergoing TACE in the backdrop of liver cirrhosis, echoing their indicative significance of the inflammatory milieu intertwined with tumor-host dynamics.

Serum inorganic phosphate levels and urinary pH levels seem to play an important role in the treatment of IESS with ACTH, and they may have indicative significance for precision treatment.

This study found that 57.4% of NTM patients showed bronchiectasis on lung CT, and 38.2% showed cavity manifestations, mainly thin-walled cavities, which have indicative significance for clinical diagnosis.