In comparing the change in treatment effect by year, facilitator enthusiasm and objectives met improved from year 1 to 2 in the intervention group (classroom control was just beyond significance when adjusted, FDR p = .052).
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p=0.06
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The same held true for ODD, with the exception of one time point, from age 6 to 8 ( β = −0.10 , p = 0.028), but this path was rendered just beyond significance when adjusting for the false discovery rate ( p = 0.052) Regarding teacher report, increased symptoms of CD predicted reduced social skills from age 6 to 8 years ( β = −0.16 , p = 0.001) only, while increased symptoms of ODD predicted reduced social skills from age 8 to 10 years ( β = −0.12 , p = 0.015) only.
Eosinophils also trended higher in RAGE TG mice compared to controls; however, the average increase was just beyond significance (p =0.06).
The top functional categories were membranes (GO:0016020) and calcium ion transmembrane transport (GO:0070588) both with p = 0.069 just beyond significance following multiple test correction.