“likely to be significant”

The terms with p -value less than α-level (0.05) were considered as having significant effect on response while the terms having p -value more than 0.05 and less than 0.1 were considered as likely to be significant.

36 , 37 , 49 , 50 , 51 , 52 Downstream repercussions of changes in tail‐anchored protein insertion in neurons are likely to be significant: mutations in the GET protein WRB, for example, result in neuronal phenotypes. 53 , 54 Thus, future validation studies investigating the consequences of changes in CAMLG expression, and of V78I, on neuronal lysosomal function and handling of “proteinopathies” such as misfolded aSyn in model systems such as neuronal culture or transgenic animals, are easy to envision and would be a valuable addition to the work presented here.

Therefore, DgFH18 and DgCMO-like are likely to be significant contributors to the regulation of flowering time in orchardgrass.

Evaluating the first examples is therefore crucial, and there is likely to be significant value in sharing learning and experiences from those embedded in the implementation.

The impact of lockdown on individuals and society as a whole is likely to be significant.

Although there appears to be an interaction effect between the groups and time course ( P for interaction < 0.001; Figure 1 , bottom left), the impact of red cell transfusion is likely to be significant, as the HD group received significantly more transfusions from T0 to T1 (Table 1 ).

Considering a statistical power of 80%, a correlation of 0.122 is likely to be significant with a sample size of 525 (female subsample size) and a correlation of 0.265 is likely to be significant with a sample size of 109 (male subsample size).

Following surgery, not all minor complications seen after doing hypospadias repair warrant an additional operation to make the anatomy “perfect.” Meatal caliber rather than position are more likely to be significant with symptoms such as spraying of the urinary stream.

In Figs 1H , 2A – 2C , 5 , S2 , S3 , S16A , and S19 , Bayesian statistics was applied to test the difference in mean synaptic efficacy and synaptic CV between two groups that follow normal distributions because the frequentist statistical tests with a large number of simulated results are likely to be significant.

Once the sexual dimorphism is developed in appendages related to reproductive behavior/barrier (i.e., grasping mechanisms) in late copepodid or adult stages ( Gilbert and Williamson 1983 ), the shape and configuration of the transformed element of the male P1 basis in the new species seem likely to be significant in terms of the taxonomic point of view, too.

14 The carbon emissions of clinical trials for neurological disorders are likely to be significant because the disease burden provokes clinical trial activity, and they use a wide range of drugs, devices and outcome measures including brain imaging. 15 17 Therefore, we set out to apply the Low Carbon Clinical Trials Group’s carbon footprinting guidance to a sample of clinical trials focused on neurological disorders.

Many of these changes were not statistically significant in the full sample, as reported above, and with the small sample sizes for those who practiced they were even less likely to be significant.

Further research into the likely impact of COLOFIT on the diagnosis of other serious bowel diseases, and the development of alternative referral pathways if the impact is likely to be significant, is therefore essential to ensure that people with these conditions are not disadvantaged.

Thus, the risk of spurious results is likely to be significant.

There are also likely to be significant variations with the communities investigated and therefore the extremely high rate of exposure estimated from this highly TB endemic community is not generalisable to other lower prevalence settings.

While all analyses focused on direct medical costs, there are likely to be significant societal costs associated with treatment of DCIS.

(1) coding regions-variants in coding regions are more likely to be significant.

A feature that consistently appeared across many material classes was more widespread (and thus more likely to be significant) than a feature that appeared in only one or two material classes.

The authors of the GDs, using the GRADE system, 20 also categorised the recommendations by their strength in two levels: strong: the majority, if not all individuals, would opt for the suggested intervention; and conditional: there is likely to be significant variation in the decisions made by informed individuals.

Aripiprazole Compared to other treatments, results for this antipsychotic were more likely to be significant and were the most consistent in terms of direction (indicating inflammatory reductions across markers in both studies).

Although a p -value cannot be assigned to this, due to the magnitude of change, this is likely to be significant and repeatable in other datasets.

Although retracting the probe minimizes potential errors arising from determining the true surface of the gel, the data indicate that contributions from the substrate are more likely to be significant in retraction.

However, since these three processes are interrelated, there is likely to be significant overlap in these defects.

An r 2 value of 0.68 equates to Pearson’s correlation coefficient ( r ) of 0.82, which is widely used as a measure of sample effect size and associated with Student’s t value of 6.87 for 23 degrees of freedom ( n -2, where n = 25), and a corresponding p value of 5.3 × 10 –7 , likely to be significant.

A difficult question for future studies is how does NOD2 function as an immune tolerance checkpoint, either in the context of Crohn’s disease or immune reactions to cancer? In the context of the findings here, how does lower NOD2 signaling increase tumor infiltration with effector CD8 T cells and the therapeutic immune response to anti-PD-1? The role of NOD2 in sensing the large commensal population of gut bacteria seems likely to be significant, since germ free mice treated with anti-PD1 mount a poor immune response to MC38 tumor cells that is restored by a defined gut bacterial mixture, with the restored response dependent upon CD8 T cells ( 64 ).