Various clinical aspects, such as physical discomfort in pregnant women, interferences caused by the infant's sleeping rhythm in the postnatal phase, or vasomotor symptoms in perimenopausal women, are also likely to be significant contributors to sleep disturbances.
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There are also likely to be significant financial and resource constraints in these contexts that could impact on the quality of care in the health sector.
Overall, the simulated mutagenesis data suggest that residues that have been found to be important for canonical STAS and anti-sigma factor protein-protein interactions are also likely to be significant in the SypA-SypE interaction.
The wizard knew the research questions of the experiment, but there were no hypotheses about group comparisons that were likely to be significant.
In addition, reductions in sleep reactivity and anxiety sensitivity by CBT-I are likely to be significant mediators that reduce the severity of insomnia [ 16 , 17 ].
The effect of TEA on water permeability in cells and tissues that express high levels of AQP1 channels is likely to be significant, given the substantial amount of water that can be moved across AQP1-expressing epithelia (for example, see data on descending thin limbs in Fig. 3 ).
This difference was not significant, but a trend was observed, and this finding is likely to be significant considering a larger sample size.
According to many proteomics researchers, more than 20% of coverage is likely to be significant [ 30 , 31 ].
The interventions in this study were conducted by midwives who received training in CBT for about 2 years, but the impact of intervention skills is likely to be significant, and they need to become more skilled with supervision.
These values are likely to be significant underestimates of variant calling quality, considering known errors in the truth set owing to the inherent limitations of reference-based variant callers (see below).
Vital signs are likely to be significant indicators of post-operative recovery, as they are accepted measures in the hospital and they can detect delayed recovery [ 13 ].
Therefore, eosinophilia, along with low CD4, CD8 T cells, and activated inflammatory response, are likely to be significant prognostic factors for the disease severity.
Here, participants highlighted variations in school contexts as likely to be significant in multiple ways to the delivery of a WSA, suggesting that these be captured in reviewing existing practice and mapping needs to understand more about existing activities and school populations.
There is also likely to be significant heterogeneity in the outcomes reported in the studies.
Hence, these indicators are less likely to be significant with more volume in the market, as that proliferates any inherent randomness. 7 Concluding remarks In the present paper we have analyzed datasets provided by Zillow [8] and FRED [13] for Japan, Germany, and Canada's historical housing prices.
Since gut microbial communities of arthropods are affected by the hosts' diet (Marinozzi et al., 2013 ), the effects of diet-related environmental factors on the identity and composition of spider gut microbiota are likely to be significant, albeit largely unknown.
The potential applications of this method are far reaching and do not only concern its speed: it should rather be seen as a necessary complement to traditional expert-based photointerpretation, adding to the latter in many cases site features which may go overlooked but are likely to be significant.
This shows that the test was likely to be significant.
Most studies on stunting in Ethiopia have focused on children aged 6–59 months, suggesting that the nutritional status of new-borns has been overlooked, but the impact is likely to be significant.
Accordingly, indirect effects containing these direct associations were most likely to be significant (see Table 3 ).
As discussed above, the influence of household type on loneliness and social isolation among older adults is likely to be significant.
Based on these observations, it is possible that certain Pfam families are more or less likely to be significant binding sites.
Usage of multiple in silico tools based on different methods and combined through a consensus approach increases the sensitivity of predictions and narrows down a large list of variants to the ones that are most likely to be significant.
To further establish the specificity of the associations between the AES profile and metabolites, we also examined whether these associations were more likely to be significant than associations between metabolomic markers and any other possible score made out of five other IDS items that did not belong to AES (see Supplementary Methods for details).
The first JEE does not fully account for several key technical areas including water, sanitation, and hygiene (WASH) activities, robust infection prevention and control (IPC) programs, and support for in community health workers; these areas are likely to be significant cost drivers in future implementation efforts and are not accounted for in these cost estimates.