There are likely to be significant differences between the clinical research environment and typical health service settings, ranging from amenities (e.g. refreshments, available seating) to staffing (e.g. ratio of staff to clients, workload, salary) to time spent at the facility (e.g. waiting in general waiting rooms).
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In the literature
In addition, it is the only detailed HIV-HBV coinfection dataset available from an Asian Genotype C population in a resource limited setting, where the future burden of HBV and HIV coinfection is likely to be significant.
There are also likely to be significant temporal and generational variations in fitness which may have profound effects on vector-virus interactions and subsequent outcomes of infections.
The biological consequences of tlDSBs remain to be elucidated, but are likely to be significant.
However, specific differences between UK and US health and welfare systems mean that there is likely to be significant differences in the cost-effectiveness of CM interventions depending on whether a service user, provider or societal perspective is taken.
With a larger sample size, factors like sex and history of contact with a TB case are likely to be significant.
In particular, the self-referral service change highlights that if people can quickly receive appropriate therapy then there are likely to be significant health benefits both immediately, and in the longer term.
Although one can test for violations of sphericity, these tests are sensitive to sample size and are likely to be significant with small violations of sphericity in large samples and, conversely, fail to reach significance with large violations of sphericity in small samples (Twisk, 2003 ).
However, Roland Schauer was an early proponent during this time of a different or at least more expansive view of sialic acids, as he clearly recognized that their unique chemical structures and skewed phylogenetic distribution was likely to be significant to diverse biological phenomena.
bicalcarata and other pitcher plant species remains unclear, but it is likely to be significant, as dipteran density is usually very high.
It should be noted that in vivo, with co-transfer of CD8 T cells (plus any endogenous type 1 immune cells), there is likely to be significant IFN-γ available to potentially reproduce the cytokine balance we created in vitro.
there is likely to be significant measurement error between observers.” [ 28 ] The authors were right: by focusing on the “hot spot” and then counting the total number of mitoses in the “hot spot” and adjacent fields corresponding to an area of 1 mm 2 , reproducibility of mitotic rate can be enhanced.
30 , 50 These will not be discussed, other than to say that they are likely to be significant with treatments that are readily acceptable to the nonmedical person, especially if heavily sold to them. 4 , 13 , 25 , 51 , 52 “What does manipulation do?” revisited There is now convincing evidence for the long-proposed activation of inbuilt inhibitory pain system(s), and as a result pain relief
Principal component analysis (PCA) conducted on the parameter values of c and d shows that the parameter d is most likely to be significant in distinguishing the siRNAs (the loadings of the parameter values on the first principal component, PC1 in Table 4 , highly correlate with parameter d ).
However the possible effects of body weight to RBED volume ratio are likely to be significant and this needs to be explored fully in future studies.
This provides additional evidence that the DSS primary filter is sensitive enough to detect pairs that are likely to be significant under GSS.
However, the protected animals from group 2 and 4 had also the highest total antibody levels and therefore we conclude that in the case of a rabies-based EBOV vaccine, high level of GP-specific antibodies that are IgG1-bias are very likely to be significant as shown for groups 2 and 4 in Figure 6B .
One implication of the species variability in DNA methylation patterns in the blastocyst is that there is likely to be significant differences between species in the genes that are differentially regulated between ICM and TE.
In summary, the health impact of RNAs in circulation seems likely to be significant, but the field is just beginning to be explored and the investigation of the area of the quantitative characterization and specific biological functions of exogenous RNA is even earlier in its development.
These are likely to be significant contributors to the variations seen in the GSM and area of plaques in this study.
Caterpillars of two lycaenid butterflies, Chlorostrymon maesites (Herrich-Schäffer, 1865) and Cyclargus thomasi (Clench, 1941), consume immature seeds of Cardiospermum corindum in southern Florida, and because they cause considerable (occasionally more than 50%) loss in production, they are likely to be significant interspecific competitors of Jadera haematoloma ( Carroll 1988 ).
The resulting impacts on animal populations are likely to be significant at both regional and global scales [3] , [4] , [5] , [6] , [7] , [8] , [9] .
The impact on local and state health departments is likely to be significant given scarce resources.
An important exception to this is the earliest time bin, in which aROC F0 and aROC choice values were equally likely to be significant across all layers.
There is also likely to be significant reduction in the availability of face-to-face Careers Information Advice and Guidance (CIAG) for some client groups.