“likely to be significant”

More generally, funding risks are ameliorated if the anticipated scientific gains are likely to be significant and not geographically specific.

However, an eGFR of 90 ml/min/1.73 m 2 was associated with an error range of 62-100 ml/min/1.73 m 2 (−31-11%), which is likely to be significant.

Nevertheless, the dendrite acts in a coordinated manner and thus the spatio-temporal distributions of different spine types is likely to be significant.

Coefficients with t -value of effect above Bonferroni line are designated as certainly significant coefficients, and coefficients with t -value of the effect between Bonferroni line and t limit line are termed as coefficients likely to be significant, while t -value of effect below the t limit line is statistically insignificant and should be removed from the analysis [ 17 ].

In more traditional case/control analyses, large bins are less likely to be significant because increasing binsize generally means more noise to mitigate the signal.

The ability to produce a large number of functional ECs from iPS cells and their engraftment potential therefore are likely to be significant value in vascular re-perfusion in ischemic tissue.

This finding is likely to be significant in the understanding of T1D, as Th17 differentiated CD4+ T lymphocytes are incapable of mediating T1D in the inducible NOD.scid model prior to acquisition of the IFN γ effector function [ 36 , 37 ].

population compromised by MetS, the health impact of oxidant and particulate air pollutants in this sensitive population is likely to be significant.

Given the differing levels of resources and inequality in incomes which persist in the South African context ( May, 2000 ) and the transitory nature of SES within this setting ( May and Woolard, 2007 ), the possible ways in which SES may alter these relationships is likely to be significant.

Further support comes from the number of selected genes being smaller with randomized vs observed phenotypes (3–7 vs 14, Supplementary Figure 12 ), albeit not zero, consistent with the above MAF significance correlation resulting in SNPs with a high MAF not only to be more likely to be significant with observed phenotypes, but also with random phenotype permutations.

However, the improvement in efficiency, quality of care, public satisfaction and healthcare policy-making is likely to be significant.

This is likely to be significant: the screen was carried out at high throughput, the phenotypes examined were fairly crude and, at least in the case of the manual phenotyping, differences needed to be quite large for us to detect.

However, it is likely to be significant that the corresponding region in hOGA has the atypical sequence Thr852-Asp853-Pro854-Ser855-Val856-Ala857 (Fig. 5 ▶ ) compared with the GNAT family, suggesting that AcCoA may not be a substrate of hOGA.

STAT6 is likely to be significant in determining the nature of genes that are regulated by STAT6 in these tissues.

While the placenta undoubtedly makes an important contribution to the plasma CX3CL1 concentration, synthesis of this chemokine by maternal blood mononuclear cells and other tissues is also likely to be significant, although the exact extent remains uncertain.

IUGR is likely to be significant, as the phenotype was associated with fetal demise.

The medical and economic impact of improving CD diagnosis is likely to be significant, and our findings support further studies into the role of personalized GRS's for other strongly heritable human diseases.

There are additional countries that have highly productive (or potentially so) agricultural lands that have much slower growth in productivity; these countries are likely to be significant global players in crop production in coming years.

Associations were less likely to be significant in models that controlled for demographic and family characteristics or family/parental connectedness.

21 The introduction of additional potent steric zipper motifs by the disease-causing mutations in a PrLD is likely to be significant for two reasons.

Furthermore, there was a close association between AR and asthma in children with a history of asthma ( P <0.01, OR=4.88) or eczema ( P <0.01, OR=1.49), suggesting that both asthma and eczema were likely to be significant concomitant risk factors for AR. 37 Another recent random, multi-stage, cluster sampling study by Wang and colleagues 23 analyzed the correlation between AR and bronchial asthma or AD in a cohort of 1,524 individuals from several regions of northern China.

The annual cost per head caused by oriental theileriosis is likely to be significant, and seems to be similar to the annual cost of AUD 227 per head due to T. parva in Tanzania [ 28 ].

Our study population consisted of individuals with and without healthcare training and, as all participants were identified from the social media network of University of Birmingham students, there is likely to be significant responder bias towards a higher educated population.

This is a difficult to engage subgroup of patients and there is likely to be significant unmet social and mental health needs.

Although both series have been successfully used to block FFA1 responses in rodent insulinoma cell lines ( 25 , 51 ), we find that, at least in a Ca 2+ mobilization assay, although GW1100 has similar activity at human and rodent orthologs, the Pfizer compounds are significantly human selective ( Figure 1 ), suggesting that there are likely to be significant species ortholog issues to be considered when using these FFA1 antagonists in nonhuman systems.