Barely Significant
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may be significant

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In the literature

The Half-Maximum Effective Concentration of Guanosine and Deoxyinosine Given that guanosine and deoxyinosine may be significant (and potent) components of ceAF that may mimic the wound healing capacity of ceAF, we first explored optimal doses, i.e., half-maximum effective concentrations (EC50), that were determined using two cell lines, including keratinocyte (HaCaT) and fibroblast (HUF) cell lines for in vitro studies (CCK8 assays).
A report of Crile’s case has not been available for study, but a review of Munro’s, Kummel’s, and Lozano’s reports brings out certain points in the technic employed in each of these operations, which may be significant in relation to the outcome.” When referring to the contribution made by Lozano’s technique, he says: “Lozano applied clamps (without rubber coverings) to the very sclerotic aorta above and below the aneurysm before opening the sac.
While this effect may be significant for short TEs, our relatively long TEs (i.e., > 73 ms) and diffusion times (Δ = 22 ms, δ = 8 ms) used in this study (compared to the small intra-axonal space where the restricted diffusion process takes place) indicate that a mono-exponential signal relaxation is expected for the spins inside each axon.