The adjustment cannot completely remove all of their confounding effects and residual confounding effects may be significant.
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In the literature
More importantly, amplification of these genes was significantly related to worse survival, suggesting that these amplified genes may be significant predictors of poor prognosis and potential therapeutic targets in gastric cancer.
cerevisiae , there may be significant differences in the way fluconazole efflux pumps are regulated.
The involvement of Helicobacter bilis infection may be significant in biliary tract malignancies [ 48 ].
This may be significant as others have found SCRIB cooperates with MYC for transformation and mislocalization of SCRIB within the cell, sufficient to promote cell transformation [ 59 ].
[ 30 , 31 ] These data implied that the Actinomycetota , particularly Streptomyces in soil and human environments may be significant producers of DMS via the S ‐methylation of H 2 S and MeSH (Figure S3 , Supporting Information).
( 14 ) confirmed the role of IGF-1 as an important autocrine or paracrine regulator of smooth muscle cell proliferation, and suggested that it may be significant in determining the cellular response in rat aortas after balloon denudation.
This region may be significant for intracellular processing and trafficking during protein synthesis ( 59 ).
The interaction points suggest that these compounds may be significant in the primary treatment of psoriasis.
In lieu of interfering with the production of inflammatory mediators and/or interfering with specific inflammatory entities, there may be significant opportunities to improve outcomes in COVID-19 patients by modulating important downstream effectors of these inflammatory signals.
As such, there may be significant nuance to the outcomes associated with neurotherapeutic modulation of hyper dopaminergic states.
Firstly, the data of our study is relatively small, and the variability of the data may be significant, making it impossible to statistically evaluate the significance of the experimental results.
The retrospective nature of our study also did not allow us to collect data on exercise habits and behavior which may be significant in this group of young patients and could better help explain our findings.
The low FVC% (p<0.001), FEV1% (p=0.032), and FEV1/FVC% (p=0.034) values in the present study may be significant in terms of showing that mixed-type pulmonary dysfunction can develop in previously healthy pediatric COVID-19 patients.
[ 15 ] showed that there truly may be significant delay to RC following NAC in the community setting, which may unfortunately reinforce perceptions that NAC delays definite treatment.
Late morbidity of re-irradiation in the base of the skull region may be significant, and a high level of clinical and radiotherapy planning expertise is required.
Second, due to the limited number of patients with previous cancers, we classified SPCs by the tissue system, and the survival rates of patients with different cancers in the same tissue system may be significant different.
If these criteria are not met, there may be significant coupling between the internal modes of the isolated mass and the “rigid body” excitations.
The results obtained may be significant in terms of prevention of the development of overweight as well as structural and biomechanical changes in the limb joints and the lumbosacral complex in hemophilia patients. 2.
For this reason there may be significant differences in serum zonulin concentrations (from undetectable to very high) occurring within minutes or hours [ 17 , 31 ].
In addition, with the advancement of technology and the deepening of research and development, there may be significant progress in this field in the next five years.
Clinically applying these exercises for shoulder joint contracture in elderly people who are forced into prolonged immobility and presenting the results may be significant.
However, we did observe a higher prevalence of plaque thickness and length in patients with cerebrovascular events, which may be significant in an enlarged sample size.
EGFR amplification/mutation and mTOR mutations may be significant resistance mechanisms associated with BRAF-targeted therapy, as signalling through the EGFR/PI3K/AKT/mTOR cascade overcomes the block on BRAF/MEK to continue cell proliferation. 116 This phenomenon should be explored further to identify the specific subsets of BRAF -mutant glioblastoma patients that may benefit from BRAF/MEK therapy alone and to clarify whether the addition of EGFR or mTOR inhibitors is required for BRAF-resistant tumours.
This may be significant for the operational interpretation of results, considering that African Anopheles typically bite at night.