“may be significant”

We hypothesized that genetic predisposition and variants may be significant risk factors for PCL tears.

However, a recent study concluded that a thin gingival phenotype and inadequate keratinized mucosa width (KMW < 2 mm) may be significant indicators for the risk of peri-implant disease [ 19 ].

Hence, modulating antioxidant enzymes and oxidative stress may be significant for NAFLD treatment.

The implication of GST polymorphisms may be significant as studies suggest that that loss of mu, pi and theta GST genes increase susceptibility to inflammatory diseases, and a genetic deficiency of GSTM1 is associated with increased susceptibility to ozone-related asthma [ 61 ] and to susceptibility to AFB1-mediated damage to human liver cells [ 62 ].

It is conceivable that these elements could bind a small molecule effector, and in this regard it may be significant that the highest atomic temperature factors are observed in helices 3 and 4, implying the mobility of these elements.

While such reactions are relatively uncommon, they may be significant for specific chemotypes that are chemically labile under acidic or oxidative conditions.

Since the in vivo infusion of ANG III increased plasma aldosterone concentration without increasing blood pressure, ANG III may be significant for the pathophysiological part of aldosterone breakthrough through the induction of aldosterone release. 5.

A comparative analysis of Manchester and Brussels concluded that both cities share a series of key factors as regards strategies to foster age-friendly environments, and that these factors may be significant in terms of applicability to other cities, particularly those related to the inclusion of ageing issues in social policies and the integration and participation of the older population in driving the age-friendly agenda [ 33 ].

The high variability in diazotrophy measurements indicates that the nitrate reduction and denitrification rates measured here may be significant contributors in the overall nitrogen balance for certain corals and at specific times.

There may be significant opportunity for external funders and conveners, including CMS, to help support those states interested in strengthening consumer engagement efforts, by sharing agency experiences and best practices and providing technical assistance.

This preference may be significant for DNA repair in vivo .

According to the alignment of these DENV-1 and DENV-2 isolates, the N290D, L402F and A473T mutations in the E gene and the R101K, G105R, D340E and L349M mutations in the NS1 gene region of the DENV-1 isolates may be significant, while these AAs in the DENV-2 isolates have not been changed ( Figure 3 ).

This may be significant because previous studies report a twofold higher hypoxic ventilatory response [ 67 ] and reduced pulmonary vascular resistance [ 68 ] in pregnant women at week 36 and weeks 36−38, respectively, relative to postpartum.

However, high pressure, corresponding to dense gas, is also very common in industrial applications, and the impact of adsorption may be significant on the gas transport process.

As it stands, all 49 targets quantified in both assays which have a significant change in thermal stability may be significant in the cell-based assay.

The impact on population kidney health of future generations may be significant.

OmRV and IMNV have acquired an extracellular phase, and the structures at the five-fold axes may be significant in adaptation to cell-to-cell transmission in metazoan hosts. status released display-pdf yes is-olf no is-manuscript no is-preprint no is-journal-matter no is-scanned no is-retracted no Received 2016 May 19; Accepted 2016 Aug 23; Collection date 2016.

This may not be the case, as suggested by Myint [ 18 ], who argues that there may be significant variations in the spatial distributions, patterns, associated functional characteristics, and centrality of socioeconomic factors in urban systems.

For breast cancer in mothers, baseline rates of any breastfeeding at 6 months after birth were used, as evidence suggests that the effect of breastfeeding on the incidence of breast cancer may be significant from 6 months of breastfeeding onwards [ 17 , 18 ].

However, this study did not differentiate between molecular and serological studies when addressing these factors, which may be significant regarding the circulation of this parasite.

Therefore, there may be significant variability in age-related events among muscles.

The later may relate to potential variations in some quality attributes of the “in house” reference standards that may be significant for ADCC, but may not have such an effect on other rituximab bioactivities, i.e., different glycosylation profile may affect ADCC activity as described before, 37,38 but may be less likely to affect CDC activity or target cell binding. 39,40 The higher intra-laboratory variability (7–36%) for ADCC compared to CDC, cell-based binding or apoptosis assays (3–17%) may also reflect specific challenges of the ADCC bioassay.

The study was conducted only in Paraná, and although there is no reason to believe that there may be significant differences with other states, the data should be validated before generalization.

A 2–3-point drop or more in SAGE scores in 12–18 months may be significant and should trigger the provider to consider additional diagnoses, evaluations, or management changes.

A number of studies have previously estimated the time to perform remote and in-person device checks, yielding a wide range of time estimates, suggesting that there may be significant clinic-to-clinic variability [ 14 , 31 - 33 ].