“might be significant”

From Figure 5 we find that even when the effects of changes in transcription initiation on the response of the biphasic amplitude filter are slight, the change in the fluctuations of the protein numbers of the output gene might be significant.

In the initial steps of pathogenesis of melanoma the alterations in expression and activity of DPPIV might be significant: a) During malignant transformation of melanocytes into melanoma cells, down-regulation of DPPIV expression and later complete loss of expression occurs [ 13 , 14 , 17 ]; b) DPPIV gene is localized in chromosome 2q24.2, interestingly this chromosome is altered in 35% of melanoma specimens, indicati

It might be significant that the breakpoints in MCF7 occur in and/or truncate BCAS1, possibly explaining its total lack of expression in MCF7 cells despite being amplified [ 27 ].

On the basis of these findings, the authors proposed altered balancing between C acnes and S epidermidis might be significant in AA, prompting other researchers to suggest a protective role for S epidermidis in development of AA ( Lousada et al, 2021 ).

To another it might be significant that it is the nurse, Walton, and not Victor, who witnesses and articulates this paradox, reminding us that an ethics of caring and speaking-with is by no means the exclusive province of physicians, and in fact has been developed most fully and profoundly in the nursing literature (Lachman 2012 ).

Second, some other parameters that might be significant predictors of HBS, such as bone mineral density and bone tissue morphometry, were not routinely measured.

The protein plays a crucial role in B cell receptor signaling and might be significant for the development of the B cell repertoire as well as mature B cell function. 13 , 14 Furthermore, BLK is involved in the immune tolerance of B lymphocytes, affecting the function of B cells, which may lead to autoreactive or regulatory cellular responses, increasing the risk of autoimmune diseases.

However, a recent study showed that KIR2DS4 exhibits peptide selective binding to HLA-C which might be significant for the NK cell response to human bacterial infections ( 32 ).

As described above we were able to capture interactions which were not significant within the context of pairwise comparison but might be significant when considered along the entire spatial axis.

confirmed that some gene polymorphisms might be significant in the East Asian population but not in the European population [ 81 ].

School nurses are viewed as professionals who might be significant actors in the promotion of youth health.

In the vast majority of cases, the number of active phages applied to the patient does not exceed 10 7 PFU/ml 6 , 10 , i.e., it is below the “safe” threshold, and the effect might be significant.

In conclusion, combination of targeting both mTOR and Mnk/eIF4E signaling pathways to enhance effectiveness of mTOR-targeted cancer therapy might be significant innovation for the personalized treatment of NSCLC. non-small cell lung cancer (NSCLC) mTOR eIF4E Mnk1 apoptosis pmc-status-qastatus 0 pmc-status-live yes pmc-status-embargo no pmc-status-released yes pmc-prop-open-access yes pmc-prop-olf no pmc-prop-manuscript no pmc-prop-legally-suppressed no pmc

These findings suggest that the basal ganglia play a role in learning within the Wade and Holt videogame task, and that its recruitment might be significant in supporting changes in cortical representations of the to-be-learned sound categories.

Light blue cells: although the ratio of reproducible expression did not fulfill the criteria, the highly restricted expression pattern might be significant.

Some studies have suggested that poor environmental sanitation and housing conditions, as well as lack of appropriate control measures might be significant risk factors for malaria parasite burden [ 9 ].

Generation of hydroxyl radicals in BSA/AuNPs might be significant for the biomedical applications of such systems.

Thus, taking this point into consideration, the gp41 induced immunosuppression might be significant when the load of infectious virus is much lower than 1 × 10 6 /ml.

These interactions might be significant during the initial adsorption stages or contribute to the adsorbed layer's overall stability.

These processes might be significant in marginal seas (tidal currents are about 10 cm/s in the area 36 ).

Our findings indicated that PheDof1 , PheMADS14 and several miRNAs might be significant regulators in moso bamboo flowering and flower development.

So they might be significant targets for remedial interventions through their alternation or elimination.

Risk Factors of PVST in Patients With IBD A total of two studies demonstrated that disease duration and colorectal surgery might be significant risk factors of PVST ( 22 ), but not age, sex, body mass index (BMI), IBD location, corticosteroids therapy, smoking, or family history of IBD ( 37 ).

Perhaps unexpectedly given their cytolytic nature, EVs may establish a persistent infection within the CNS, and the lasting effects on the host might be significant with unanticipated consequences.

However, patients on hemodialysis or pre-dialysis CKD frequently have indwelling catheters and in these patients, these organisms, which are otherwise considered as cultural contaminants, might be significant pathogens, causing biofilm formation and leading to device-related bloodstream infections.