Barely Significant
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might not be significant

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p=0.0619

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In the literature

Therefore, the combination of diverse source domains in a single common domain helps to enlarge the data distribution and confirms the effectiveness of SUDA methods in certain cases [ 27 , 41 , 59 ]; however, the improvement might not be significant or guaranteed in many domain-shifting tasks.
Since the majority of classes 1 and 2 were patients with early stages of CKD (stages 1 and 2) at enrollment and half of them had CKD stage 1, factors that are previously known to be related to a rapid GFR decline other than proteinuria might not be significant in patients with stage 1 CKD.
Considering that the incidence of sporadic CRC in Korea and many countries has gradually increased recently, which is shown in our data ( Supplementary Table 1 ), the excess risk of CRC in UC might not be significant any longer, except for UC patients with severe disease activity.
The I 2 statistic values were interpreted with a 95% confidence interval (CI) as follows: 0 to 40% might not be significant, 30 to 60% might indicate moderate heterogeneity, 50 to 90% might represent substantial heterogeneity, and 75 to 100% could represent a significant amount of heterogeneity [ 25 ].
Heterogeneity was evaluated using Cochrane’s Q-test ( P < 0.10) and I 2 statistics, with interpretation thresholds set as: 0%–40% (might not be significant), 30%–60% (moderate), 50%–90% (substantial), and 75%–100% (considerable) according to Cochrane Handbook guidelines ( Cochrane Collaboration, 2024 ).