“of borderline significance”

Additionally, factors like educational level, lack of breastfeeding, stressful life events [ 1 ], gestational diabetes [ 19 ], and employment status after delivery have been found to be of borderline significance [ 8 ].

Relative to those without chronic pain, participants having 2, 3, and 4 pain sites and pain ‘all over the body’ had a 29%, 27%, 30%, and 37% higher risk of incident AD in the fully adjusted model, respectively, of which 4 pain sites and pain ‘all over the body’ were of borderline significance (Fig. 3 and Table 2 ).

However, the association between the current use of atypical antipsychotics (AAP) and the mortality was of borderline significance, and there was no significant difference for past users of AP.

5 In accordance with our results, this study also found that, although the association was significant among participants <65 years of age (HR, 1.29; 95% CI, 1.17–1.43), the association was weaker and of borderline significance among participants ≥65 years of age (HR, 1.08; 95% CI, 0.99–1.17). 5 In line with our findings, another study in Singapore, composed of 77% Chinese, 15% Malays, and 6% Indians, demonstrated that, although prehypertension was associated with CVD mortality, the risk estimate did not reach statistical significance (HR, 1.5; 95% CI, 0.8–2.6).

The results for biologically verified complete cessation suggested that participants in the snus group were more likely to quit smoking completely than the controls; the odds ratio (snus versus placebo) for the protocol estimates of cessation varied between 1.9 to 3.4, but these ratios were of borderline significance with p-values ranging from 0.04-0.10.

Although the similarity in disease behavior, defined as non-stricturing non-penetrating disease, stricturing disease or penetrating disease, was of borderline significance only, concordance in disease behavior has been confirmed more recently in the combined Swedish–Danish twin cohort [ 63 ].

26.8), whereas an advanced stage was of borderline significance (median 20.6 vs . 25.8 months).

The combination of elevated tHcy and Lp(a) was only of borderline significance in its association with stroke which may be due to the limited numbers of cases and participants with this biomarker combination.

Cox regression analysis showed that Ki-67 was of borderline significance as an independent predictor for DFS.

Newborns of women with PAC diagnosed during pregnancy had a higher risk of borderline significance of a low Apgar score (aPR=2.65, 95% CI: 0.96–7.33) as compared to cancer-free women.

Sensitivity analysis The intervention group’s doubled rate of validated cessation at four weeks after discharge was of borderline significance.

All scores were converted to T-scores corrected for age, education, and gender according to the FrSBe administration manual [ 25 ], T-scores < 60 are considered normal; scores of 60-64 are considered of borderline significance, and scores of 65 or above are considered clinically significant.

Nevertheless, we are extremely cautious about making conclusions from such subtle changes of borderline significance, as these likely represent Type 1 errors.

Clinical tumor size and invasive lobular carcinoma were of borderline significance.

In ezetimibe-treated animals the GPx decrease caused by I/R was of borderline significance (E-I/R vs.

The remaining studies provided either more indirect evidence of the benefits of treatment for preterm delivery ( 54 ), mixed results depending on the specific analysis ( 5 ), or evidence of borderline significance [( 28 ); Table 2 ].

Other studies have examined associations between MPM risk and the pigmentation pathway by assessing variations in MC1R 18 – 20 and MITF 21 , as well as vitamin D synthesis among individuals exposed to high levels of sunlight in recreational activities 22 , although these results were of borderline significance.

Multivariate and stratified analyses of fixed-facility events Results from the multiple regression analysis of temporal variables indicated an association of borderline significance between fixed-facility events with victims and the three-way interaction indicated by time of day (0600–1159), day of week (weekday), and season (March through May) (p = 0.06); no interaction among temporal variables was indicated for evacuations.

44 The association between Lp(a) and coronary events was of borderline significance and primarily driven by the number of revascularization procedures as well as angina/ischemia requiring hospitalization or myocardial infarction.

Although AKT was of borderline significance, mTOR demonstrated no significant changes (Fig 3 A).

Additionally the study confirmed 24 previously established RA loci and further findings of borderline significance were reported that will require further validation.

At multivariate analysis, HER2/ neu over-expression and Ki67 ≥ 20% were independent predictive factors of brain relapse and endocrine unresponsive tumours (both ER and PgR < 10%) showed an increased risk of central nervous system recurrence of borderline significance.

Patients had no statistically significant difference in BMI, total cholesterol, LDL cholesterol and triglycerides, and in the incidence of cigarette smoking, whereas the difference in the HDL cholesterol level was of borderline significance.

There was only a small enrichment of borderline significance in the ORF of TGFBR2 , but after removal of sequences with a seed match to the TGFBR2 3' UTR, the signal became significant (see Additional File 1 Figure S4).

The odds of having VI was higher among women (OR 1.2; 95% CI 1.0 to 1.4) compared with men though it was of borderline significance.