“quite significant”

Pneumococcal vaccination in HF is also quite significant, as shown by clinical trials.

As we can see, the differences are quite significant, and all the alternative parameter assignments lead to a substantial underestimation of the experimental isotherm.

Maldigestion and Malabsorption The nutritional elements that are malabsorbed are numerous and their clinical consequences are quite significant.

However, each of them has quite significant drawbacks.

Therefore, not just a simple reduction in the use of plastics, but especially suitable practices in the recovery, reuse and recycling of plastics, would help in mitigating the problem to a quite significant extent; another possible way (which can be seen as an alternative or, at least, as a complementary way) might be based on the use of biodegradable plastics (additional discussion will be given in a following section of this paper).

Similarly, all of these changes may be quite significant for diminishing psychomotor and cognitive functions during this month.

There is quite significant prevalence of enzymatic resistance against the broad-spectrum anti-bacterial drug cephalosporins [ 4 , 5 ].

Conversely, in XP490, where resistance took the longest (6 to 8 mo), mTORC1 inhibition in nontumor cells accounted for a proportionally smaller, though still quite significant, effect.

More to it, the intra-seasonal variation in rainfall is quite significant.

The enrichment of IFN-γ + CTLs was quite significant and is comparable to recently published vaccination systems based on nucleic acid materials ( 40 , 41 ).

In contrast, the Cu C site, which was previously believed to be the active site, copper has one negative ligand, leading to a probable Cu(II) oxidation state in that case, which is a quite significant difference.

In addition, the potential of disseminating multidrug-resistant bacteria (MDR) into the population is quite significant, posing a serious public health risk resulting from improper sewage disposal and treatment.

This document seems to be quite significant for European surveillance operations.

to carbapenems is quite significant, with a reduction from 79.2% to 10.4% between 2012 and 2021.

This anti-inflammatory activity of POA is quite significant when assessed in cells of the innate immune system, where it is generally comparable to that of omega-3 fatty acids [ 25 , 26 ].

All of the above-mentioned issues are quite significant in clinical practice.

Interestingly, during the development of seeds and siliques, the expression levels of four genes ( BnANDPK5b , BnANDPK8b , BnCNDPK4b , and BnCNDPK7b ) from the NDPK I subfamily were quite significant, indicating that the NDPK I subfamily may be an important subfamily within the NDPK family and could play a key role in plant growth and development, consistent with previous research [ 17 ].

There was a sense that a lack of adequate resources was potentially leading to less positive outcomes for clients than might otherwise be achieved: “I think it’s true of all aspects of the NHS, but resources, you know, not having enough people to be able to see patients and have, you know, particularly people with quite significant cognitive impairment, you would want to be able to do repetition to try and support some need to improve and cope and build strategies, but if you don’t, you’re not able to do that repetition because you don’t have adequate staffing to do that either as an inpatient or an outpatient.

The density of the material with an equal volume share of magnetite aggregate (CM1-2 ÷ CM8-16), shows quite significant fluctuations, with a clear increase with the grain size of the aggregate.

Yet, we cannot draw certain conclusions as the included studies were quite few, and the degree of heterogeneity was quite significant. 5.

Therefore, determining and monitoring DA levels in real time is quite significant and can be used not only for early diagnosis of diseases but also for evaluating the effectiveness of various drugs in DA manipulation.

From both a clinical and public health point of view, it was particularly frustrating as this study documented the efficacy of nirservimab in a specific and quite significant subset of patients, i.e., admission to PICU [ 87 , 117 , 118 ], the prevention of which would lead to a substantial reduction in the eventual RSV-associated disease burden in terms of both morbidity and direct and indirect costs.

Thus, and as you have suggested, even though the mortality isn’t very high, the impact in the Loss Gap is quite significant.

One of the uncommon but quite significant causes to be considered are kidney and urinary tract stones.

The contribution of the fast component is quite significant in this case as well.