From the pharmacodynamics aspect, the results of the current study showed a slightly non-significant difference between the fast and fed groups indicating the absence of clinical effect of food on the pharmacodynamics of indapamide in compliance with what was reported in the literature regarding the probable food effect on indapamide clinical efficacy [ 13 ].
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“slightly non-significant”
In the literature
There were slightly non-significant negative correlations between S_CMD 3 s and C_CBSD 3 s ( r = −0.07), C_CBSD 6 s ( r = −0.05), and C_CBSD rs ( r = −0.03) ( Table 4 ).
Women had a slightly non-significant higher median discharge INR compared with men.
Additionally, there was a slightly non-significant increase of SREBP expression in the animals exposed to DDVP and MNU compounds (DDVP, MNU, and DDVP + MNU groups), compared to the Control group. 4 Discussion Worldwide, prostate cancer is the second most frequent cancer and the fifth leading cause of cancer death among men, making it a major public health problem ( Sung et al., 2021 ; Siegel et al., 2023 ).
Notably, the oral administration of SA along with Cr showed a slightly non-significant reduction in the expression of HSP70 protein, while the expression of caspase-3 was significantly reduced (p ≤ 0 . 05) upon administration of SA in group IV, compared to the Cr-intoxicated group.
The results of the UKPDS trial, which enrolled more than 3000 diabetic patients without cardiovascular disease at baseline and followed-up for 10 years, demonstrated the importance of tight glycemic control (defined as fasting blood glucose < 100 mg/dl) in reducing the incidence of microvascular complications, and with a trend toward a slightly non-significant 16% relative risk reduction in myocardial infarction.
Comparing perceived health status between genders showed a slightly non-significant higher value in men, consistent with previous studies showing a worse self-perception of health in women [ 18 ].
Homozygous VLCADD variants showed slightly non-significant differences of relevant acylcarnitines in comparison to compound heterozygous variants (Fig. 5 , due to small sample size no statistical analysis was performed).
Remarkably, the highest inhibition was attained with 1000 μg/mL of HAE at the third day (~70%), with 500 and 1500 μg/mL inducing slightly non-significant lower values (65% and 64%, respectively).
The analysis based on six RCTs showed a slightly non-significant difference in the incidence of uveitis between JAKi and the placebo (incidence rate ratio [IRR] 0.32, 95% CI 0.06–1.67; moderate certainty, Table S20 ) [ 120 ].
With regard to graft function, we found a slightly non-significant higher rate of renal DGF in the group of nighttime surgery.
Nevertheless, a slightly non-significant decrease in antibody response was visible in the therapeutic paracetamol group compared to the control group.
4 Also, there is a documented slightly non-significant protective effect of cesarean deliveries, 3 favoring the hypothesis that the anatomical changes due to labor may maintain the exposition of the transformation zone and enhance the metaplastic process.
It is worth noting that men showed higher correlation coefficient values than women (significant when comparing the 95% confidence intervals), as well as slightly non-significant superior correlation values for data collected in Medellín and those with high levels of physical activity ( Figure 2 ).
europaea showed slightly non-significant decreases at low and moderate treatments and significantly decreasing at higher concentrations.
After BU antibiotic therapy, there was a slightly non-significant improvement in the IFN-γ response of the BU-HIV coinfected patients.
The use of 6–12 mmol of NO 3 − contained in beetroot juice supplements produced significant improvements in time to exhaustion in a 5–30 min cycling race, but slightly non-significant improvements in time trial or graded-exercise performance [ 80 ].
The current study showed slightly non-significant gender differences in survivors’ perception of QoL and mental illness (Tables 5 and 6 ), which may be explained by the small sample size.
In contrast to the TV group, the BM group exhibited a slightly non-significant narrowing of the esophageal lumen at the level of the reconstructed region, as detected by the values of the ARLD between the patched area and the same area preoperatively ( Fig. 3 ).
Total white blood cell (WBC) counts, indicative of significant inflammatory processes, increased significantly ( p < 0.05) in all DSS-exposed groups, with slightly non-significant higher counts in the non-treated group, compared to the f-hPSCs IP-injected mice ( Figure 2 C).
Although the results showed slightly non-significant increased weight among fetuses of T3 (totally or based on the fetus sex) compared to the control group (C2), T4 group had statistically decreased weight compared to control group.
Sunitinib treatment in a concentration of 0.5 μM resulted in an enhanced, but slightly non-significant, activity of AKT and a significant enhanced activity of all other signaling molecules investigated.
Patients may suffer mild impairment of cognitive and motor functions before they can be properly diagnosed with MHE, as supported by the slightly non-significant poorer performance of NMHE patients in many parameters and in the PHES subtests being an indication of this.
Hospital porters did not show a higher or lower likelihood compared to office staff (OR 1.00; 95% CI 0.33, 3.04), whereas ambulance men showed a slightly non-significant increased OR of 1.28 (95% CI 0.49, 3.34) compared to office staff [ 47 ]. 3.4.
Similarly, including gender as a covariate in the mediator model rendered the indirect effect slightly non-significant (left VS activity on BMI through both HOMA-IR and leptin: 95% bootstrap confidence interval of −0.97 to 49.34).