Learnings about Aβ from human brain recommend the use of a live-neuron bioassay for the discovery of next generation Alzheimer's disease immunotherapeutics.

Acta Neuropathol Commun · 2023 · PMC10007750 · PMID 36899414

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a strong trendno p-value reported

did not reach statistical significanceno p-value reported

At 5 μg/mL, SAR also showed a strong trend to attenuate synaptotoxicity, but this protection did not reach statistical significance (Fig. 6 B, D).

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