In UC patients, consumption of the strain for 6 weeks was associated with significantly reduced CRP levels compared with the placebo group ( p = 0.0327), while the reduction in IL-6 levels approached significance ( p = 0.057).
acidophilus , Lactobacillus rhamnosus (now Lacticaseibacillus rhamnosus ), and Saccharomyces boulardii showed a trend toward lowering NEC (4% versus 12%) in very low birth weight neonates in a randomized, double-blinded controlled trial where breast milk served as the control (no placebo included). 74 However, the authors suggest that the use of breast milk in the control group may have narrowed the differences between the two groups given the beneficial properties associated with breast milk.