Association of <i>HLA</i>-<i>class II</i> alleles with risk of relapse in myeloperoxidase-antineutrophil cytoplasmic antibody positive vasculitis in the Japanese population.

Front Immunol · 2023 · PMC10030796 · PMID 36969218

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showed a trendno p-value reported

In our study, HLA-DRB1*09:01 , - DQA1*03:02 and - DQB1*03:03 , the susceptibility alleles for MPO-AAV in East Asian populations ( 12 – 16 ) showed a trend toward a higher risk of relapse of MPO-AAV in a Japanese population, possibly suggesting that the susceptibility alleles for AAV may also be associated with relapse in each ethnic group.

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did not reach statistical significanceno p-value reported

These alleles showed a trend toward protection from relapse, although the differences did not reach statistical significance.

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