Quantification of tumor lesions at 26 weeks after Ad-Cre inhalation revealed that Rb1 FL/FL Tp53 FL/FL Rela FL/FL mice showed a trend toward reduced tumor presence compared to Rb1 FL/FL Tp53 FL/FL mice, which however did not reach statistical significance (Fig. 3C ).
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NEMO- and RelA-dependent NF-κB signaling promotes small cell lung cancer.
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