In this study, we confirmed that MmuPV1 E7 interacts with PTPN14 and showed a trend towards causing reduced steady levels of PTPN14.
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MmuPV1 E7's interaction with PTPN14 delays Epithelial differentiation and contributes to virus-induced skin disease.
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The sentences
We detected a slight (~2 fold at passage 2 and ~3 fold at passage 10) increase in E7 K81S mutant viral genomes compared to wild type viral DNA, but this difference did not reach statistical significance.