Neutrophil Extracellular Traps and Platelet Activation for Identifying Severe Episodes and Clinical Trajectories in COVID-19.

Int J Mol Sci · 2023 · PMC10094814 · PMID 37047662

Europe PMC DOI

hedged sentences

0.0660

closest p · 1.3× alpha

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boldest claim

The sentences

did not reach statistical significancep = 0.066so close (0.05 < p ≤ 0.1)

NETs, Platelet Activation and Initial Severity CitH3, cfDNA and P-selectin levels were higher in ICU-admitted patients; however, P-selectin levels did not reach statistical significance ( p = 0.066; OR 2.45 [95% CI 0.95–6.44]) ( Figure 1 ).

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showed a trendno p-value reported

Secondly, higher cfDNA (a non-specific marker of NETosis) levels also showed a trend for identifying transitions to more severe states, whereas lower levels were associated with transitions to more favorable clinical states.

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