In addition, there was substantial variability within the different treatment groups, and the results of this assay did not reach statistical significance.
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The novel estrogen receptor modulator STX attenuates Amyloid-β neurotoxicity in the 5XFAD mouse model of Alzheimer's disease.
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Likewise, a correlation analysis identified positive relationships between MWM responses and several pathological markers that were significant or approached significance in females, while this relationship was less robust in males ( Table 1 ).